Individual Differences in Blood Pressure Reactivity and Behavior of Male Rats

  • J. M. Koolhaas
  • D. S. Fokkema
  • B. Bohus
  • G. A. van Oortmerssen


One of the major concerns in research on the aetiology of coronary heart disease (CHD) and hypertension has been the question why some individuals suffer from these diseases while others are healthy, although exposed to seemingly identical external conditions. Since the early studies by Friedman and Roseman (1959), it has become increasingly clear that apart from environmental circumstances, personality factors are also important. In order to study the complex interplay between environmental variables and personality factors in the pathophysiology of the cardiovascular system, animal research is indispensable.


Squirrel Monkey Blood Pressure Response Blood Pressure Reactivity Dominant Animal Basal Blood Pressure 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • J. M. Koolhaas
  • D. S. Fokkema
  • B. Bohus
  • G. A. van Oortmerssen
    • 1
  1. 1.Department of Animal PhysiologyState University of GroningenHarenThe Netherlands

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