Metabolism and Acute Toxicity of Volatile Anesthetics
It is well documented that the halogenated methane derivatives CCl4 and to a lesser extent CHCl3, and therefore also the anesthetic chloroform, which was used until well into the sixties, are hepatotoxic . There is also good reason to suspect that halothane might also occasionally cause liver reactions leading to lethal hepatic necrosis .
KeywordsToxicity Hepatitis Chloroform Fluoride CHCl3
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