Abstract
The development of leg ulcers is attributed to disturbed skin microcirculation, which is said to be the result of an increase in capillary pressure with the leaking of blood components through the capillary wall and the formation of a specific microedema [5]. Transcutaneous oxygen pressure measurements in the vicinity of ulcers yielded low values in both venous and arterial ulcers [1]. This is explained by a rarefication of capillaries [8]. In contrast, patients with liposclerosis or venous ulcerations show a marked proliferation of capillaries in the subcutaneous tissue [3]. Around the capillaries, fibrin walls are found, which act as diffusion barriers for oxygen [2]. Local hyperemia is observed after positron emission tomography and measurements of the blood flow in the skin using the laser-Doppler method [7, 10]. We have determined the tissue oxygen pressure in leg ulcers.
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Creutzig, A., Wuppermann, T., Hanauske, U., Alexander, K. (1987). Tissue Oxygen Pressure in Ulcers of the Lower Leg. In: Ehrly, A.M., Hauss, J., Huch, R. (eds) Clinical Oxygen Pressure Measurement. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71226-5_8
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DOI: https://doi.org/10.1007/978-3-642-71226-5_8
Publisher Name: Springer, Berlin, Heidelberg
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