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Transcutaneous PO2 and PCO2 During Sleep in Patients with Chronic Obstructive Lung Disease Under Different Modes of Therapy

  • K. H. Rühle
  • G. Klein
  • M. Schmitz-Schumann
  • H. Matthys
Conference paper

Abstract

Patients suffering from chronic obstructive lung disease (COLD) frequently develop hypoxemia, i. e., oxygen desaturation, during sleep. This is caused by ventilation/perfusion inhomogeneity [1] or by diminished ventilation with a reduction in the tidal volume or the respiratory rate or apneic episodes (Fig. 1). It can be treated by raising the inspiratory oxygen concentration by administering 100% oxygen through a nasal prong [3]. Another possibility is stimulating the respiratory center with centrally acting respiratory analeptics. We now have a drug at our disposal which stimulates the peripheral chemoreceptors and, particularly in the case of hypoxia, increases ventilatory drive.

Keywords

Oxygen Desaturation Chronic Obstructive Lung Disease Inspiratory Oxygen Concentration Ventricular Ectopic Beat Peripheral Chemoreceptor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • K. H. Rühle
  • G. Klein
  • M. Schmitz-Schumann
  • H. Matthys

There are no affiliations available

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