Tissue PO2 Measurements in Critical Care: The Effects of Dopamine on Muscular Oxygen Pressure Fields

  • T. Kersting
  • K. Reinhart
  • W. Fleckenstein
  • R. Dennhardt
  • K. Eyrich
  • C. Weiss
Conference paper


In critical care medicine, dopamine is used for treatment and prevention of circulatory insufficiency and shock [5, 7, 13, 20]. At low doses (2 to 5 µg/kg per min) renal blood flow and sodium excretion are increased [1, 5, 6, 12, 13, 14, 18, 19, 22]; these effects are attributed to the action of specific dopamine receptors [5, 16, 23]. At higher doses (5 µg/kg per minute), sympathic β1 - and α-receptors are stimulated, so that cardiac output and (especially at doses over 10 µg/kg per min) vascular resistance are increased [5, 6],


Muscle Blood Flow Dopamine Infusion Lactate Content Dopamine Dose Peripheral Dopamine 
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© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • T. Kersting
  • K. Reinhart
  • W. Fleckenstein
  • R. Dennhardt
  • K. Eyrich
  • C. Weiss

There are no affiliations available

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