Abstract
The rationale, history, and results of the therapeutic application of allogeneic and syngeneic marrow transplantation in acute leukemias have been discussed in a number of reports and reviews [1, 2]. The humble beginnings with transplantation of patients with end-stage disease in the late 1950s to the early 1970s have rapidly improved to the application of marrow transplantation in the treatment of patients earlier in the course of their disease and in a situation of minimal residual disease. Most problems of leukemia relapse, graft-versus-host disease (GvHD) and viral infections have been identified, and solutions to these problems are being actively pursued in many centers around the world.
Supported in part by Grants (CA-15396 and CAO-6973) from the National Cancer Institute, Department of Health and Human Services and by a grant from the W.W. Smith Charitable Trust.
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© 1987 Springer-Verlag Berlin Heidelberg
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Santos, G.W., Yeager, A.M., Saral, R. (1987). Allogeneic, Syngeneic, and Autologous Bone Marrow Transplantation in the Acute Leukemias — Baltimore Experience. In: Büchner, T., Schellong, G., Hiddemann, W., Urbanitz, D., Ritter, J. (eds) Acute Leukemias. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 30. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71213-5_33
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DOI: https://doi.org/10.1007/978-3-642-71213-5_33
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