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Strategies for the Treatment of Children with Acute Lymphoblastic Leukemia and Unfavorable Presenting Features

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Book cover Acute Leukemias

Part of the book series: Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ((HAEMATOLOGY,volume 30))

Abstract

The Childrens Cancer Study Group (CCSG) is an association of over 100 institutions whose members are responsible for the care of the majority of children with neoplastic disease in the United States and Canada. Over the last 30 years, clinical trials have been conducted for children with acute lymphoblastic or undifferentiated leukemia (ALL). The voluminous data collected have permitted the identification of presenting features that are strongly predictive of outcome and maintain this power in multivariate analyses [1, 2]. These include age, lymphoma syndrome, white blood count (wbc), and percent marrow blasts FAB L2 [3, 4].

Grant support from the Division of Cancer Treatment, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, United States of America.

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Authors and Affiliations

  1. Childrens Cancer Study Group, 199 North Lake Avenue, Pasadena, CA, 91101, USA

    P. S. Gaynon, P. G. Steinherz, G. H. Reaman, W. A. Bleyer, H. Sather & G. D. Hammond

Authors
  1. P. S. Gaynon
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  2. P. G. Steinherz
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  3. G. H. Reaman
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  4. W. A. Bleyer
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  5. H. Sather
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  6. G. D. Hammond
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Editor information

Editors and Affiliations

  1. Departments of Internal Medicine and Pediatrics, University of Münster, Albert-Schweitzer-Strasse 33, D-4400, Münster, Federal Republic of Germany

    T. Büchner , G. Schellong , W. Hiddemann , D. Urbanitz  & J. Ritter , , ,  & 

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© 1987 Springer-Verlag Berlin Heidelberg

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Gaynon, P.S., Steinherz, P.G., Reaman, G.H., Bleyer, W.A., Sather, H., Hammond, G.D. (1987). Strategies for the Treatment of Children with Acute Lymphoblastic Leukemia and Unfavorable Presenting Features. In: Büchner, T., Schellong, G., Hiddemann, W., Urbanitz, D., Ritter, J. (eds) Acute Leukemias. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 30. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71213-5_25

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  • DOI: https://doi.org/10.1007/978-3-642-71213-5_25

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-16556-9

  • Online ISBN: 978-3-642-71213-5

  • eBook Packages: Springer Book Archive

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