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Nonsurgical Management of Wilms’ Tumor

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Renal and Adrenal Tumors

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Abstract

The extraordinary improvement in the results of treatment of Wilms’ tumor in the last 20 years is demonstrated by the fact that it has one of the highest cure rates of all malignancies in children. Even with the presence of metastases at the time of diagnosis, or in the case of bilateral Wilms’ tumor, promising therapeutic regimens have been reported [39, 7, 4]. Advances in treatment in the past decade have also improved the survival rate for patients with Wilms’ tumor. Actinomycin D and vincristine were introduced as chemotherapeutic agents, and the importance of combined surgical, radiotherapeutic, and chemotherapeutic regimens was recognized. The reason for this therapeutic progress may be summarized as follows: (a) Radical, transperitoneal nephrectomy; (b) radiotherapy to destroy residual tumor; (c) adjuvant polychemotherapy to eradicate micrometastases.

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Authors
  1. W. Havers
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Editors and Affiliations

  1. Röntgendiagnostisches Zentralinstitut, Klinikum der Universität Essen, Hufelandstraße 55, D-4300, Essen, Germany

    Eberhard Löhr

  2. Institut für Pathologie, Klinikum der Universität Essen, Hufelandstraße 55, D-4300, Essen, Germany

    Lutz-Dietrich Leder

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© 1987 Springer-Verlag Berlin Heidelberg

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Havers, W. (1987). Nonsurgical Management of Wilms’ Tumor. In: Löhr, E., Leder, LD. (eds) Renal and Adrenal Tumors. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71207-4_15

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  • DOI: https://doi.org/10.1007/978-3-642-71207-4_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71209-8

  • Online ISBN: 978-3-642-71207-4

  • eBook Packages: Springer Book Archive

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