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Chlamydia Trachomatis: Reiter’s Syndrome and Reactive Arthritis

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Chlamydial Infections

Abstract

In the last decade, substantial advances in microbiological techniques and human genetics have combined to provoke considerable interest in Reiter’s syndrome (RS) and other forms of arthritis associated with infections. As a form of “reactive arthritis” the essential component of Reiter’s syndrome is the apparent initiation of inflammatory joint and other musculoskeletal lesions by an infection at a site distant from the joint, though the inflammatory lesions themselves are sterile. Recognized precipitating infections include genital and gastro-intestinal infections, though it is likely that other types of “trigger” infection will also be identified. Other forms of reactive arthritis are associated with streptococcal tonsillitis or pharyngitis (rheumatic fever), and possibly tuberculosis (Poncet’s disease), though these differ clinically and genetically from arthritis associated with genital or gut infection.

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Keat, A.C.S. (1987). Chlamydia Trachomatis: Reiter’s Syndrome and Reactive Arthritis. In: Reeve, P. (eds) Chlamydial Infections. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71202-9_9

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