Abstract
Allergy due to papaya derivatives - whether acquired by inhalation [41], ocular [4], digested [21], or parenteral administration - has been known and reported for 40 years [47]. It is therefore not surprising that these anaphylactic reactions had been verified by the time of the advent of nucleolysis using chymopapain, which is the principal proteolytic composant of the papaya [1, 3, 7, 13, 18, 24, 38, 52, 54, 61, 62].
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Laxenaire, M.C., Monneret-Vautrain, D.A. (1986). Anaphylactic Accidents Related to Chymopapain: Prevention and Treatment. In: Bonneville, JF. (eds) Focus on Chemonucleolysis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71182-4_12
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DOI: https://doi.org/10.1007/978-3-642-71182-4_12
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