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Expression of T-Cell Receptor by a Mouse Monoclonal Antigen-Specific Suppressor T-Cell Line

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Specificity and Function of Clonally Developing T Cells

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 126))

Abstract

The antigen receptor expressed by mouse T lymphocytes is composed of a disul- fide-linked dimer of about 85K, resolved under reducing conditions in two sub-units with an apparent Mr of approximately 42K (Allison et al. 1982; Kappler et al. 1983). The antigen-specific receptor expressed by human T lymphocytes displays a similar structure, but the two subunits, denominated α and β chain, have a Mr of about 51K and 43K, respectively (Meuer et al. 1983; Acuto et al. 1983).

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© 1986 Springer-Verlag Berlin Heidelberg

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Adorini, L., Palmieri, G., Sette, A., Appella, E., Doria, G. (1986). Expression of T-Cell Receptor by a Mouse Monoclonal Antigen-Specific Suppressor T-Cell Line. In: Fleischer, B., Reimann, J., Wagner, H. (eds) Specificity and Function of Clonally Developing T Cells. Current Topics in Microbiology and Immunology, vol 126. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71152-7_7

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  • DOI: https://doi.org/10.1007/978-3-642-71152-7_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71154-1

  • Online ISBN: 978-3-642-71152-7

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