Regulation of Lytic Function by Recombinant IL2 and Antigen

  • A. C. Ochoa
  • G. Gromo
  • S.-L. Wee
  • F. H. Bach
Conference paper
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 126)


The study of signals involved in the generation and maintenance of cytotoxic T lymphocytes (CTLs) has been facilitated by the availability of various techniques based on the mixed leukocyte culture (MLC) test (Bain et al. 1964; Bach and Hirschhorn 1964). In addition to the proliferative response in an MLC, CTLs are generated (Hayry and Defendi 1970; Hodes and Svedmyr 1970; Solliday and Bach 1970).


Tissue Culture Medium Lymphoblastoid Cell Line Lytic Function Mixed Leukocyte Culture Stimulator Ratio 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • A. C. Ochoa
    • 1
  • G. Gromo
    • 1
  • S.-L. Wee
    • 1
  • F. H. Bach
    • 1
  1. 1.Immunobiology Research Center, Departments of Laboratory Medicine, Pathology, and SurgeryUniversity of MinnesotaUSA

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