Abstract
In experimental oncology multicellular tumor spheroids (MTS) serve as an in vitro model which simulates avascular three–dimensional solid tumor growth adequately (13). We succeeded in growing the malignant RG2 glioma clone as MTS. The RG2 clone is derived from a transplacen–tally N–nitrosourea induced tumor of the central nervous system in inbred CDF rats, morphologically characterized as malignant glioma and established in tissue culture (4).
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© 1986 Springer-Verlag Berlin Heidelberg
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Krajewski, S., Kiwit, J.C.W., Wechsler, W. (1986). Subdural Implantation of RG2 Glioma Spheroids in Rat Cerebellum: A New Experimental Brain Tumor Model. In: Wenker, H., Klinger, M., Brock, M., Reuter, F. (eds) Spinal Cord Tumors Experimental Neurosurgery Neurosurgical Intensive Care. Advances in Neurosurgery, vol 14. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71108-4_43
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DOI: https://doi.org/10.1007/978-3-642-71108-4_43
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