Abstract
Swelling of nerve and glial cells (cytotoxic brain edema) is a common feature in cerebral ischemia, anoxia, and other metabolic derangements of the brain. Analysis of mechanisms involved in cytotoxic edema of the living brain is impeded by the diversity and complexity of factors which are simultaneously subjected to change in pathological conditions. The availability of stable cell lines of cerebral origin as well as of novel flow-cytometric techniques for cell volume determination has enabled us to establish an in vitro model for the study of swelling mechanisms of defined cells under defined conditions (2, 5).
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© 1986 Springer-Verlag Berlin Heidelberg
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Jansen, M., Neu, A., Rosen, F.v., Kempski, O., Baethmann, A. (1986). Swelling Behavior of C6 Glioma Cells During Shutdown of Energy Metabolism. In: Wenker, H., Klinger, M., Brock, M., Reuter, F. (eds) Spinal Cord Tumors Experimental Neurosurgery Neurosurgical Intensive Care. Advances in Neurosurgery, vol 14. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71108-4_33
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DOI: https://doi.org/10.1007/978-3-642-71108-4_33
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