Comparison Between Electrophysiological Approaches for Presurgical Evaluation

  • J. EngelJr.


Electrophysiological evaluation of patients with epilepsy who are candidates for surgical resection is performed for two specific purposes. The most important is precise localization of the epileptogenic lesion responsible for most or all of the patient’s habitual seizures. The second involves functional mapping that may be required to identify primary motor and sensory cortical areas that cannot be removed without producing unacceptable neurological deficit. Considerable controversy exists concerning the necessary and sufficient electrophysiological studies for both localization and functional mapping, and a variety of approaches are currently utilized.


Temporal Lobe Epilepsy Functional Mapping Depth Electrode Presurgical Evaluation Anterior Temporal Lobe 
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  1. Ajmone-Marsan C (1980) Depth electrography and electrocor-ticography. In: Aminoff MJ (ed) Electrodiagnosis in clinical neurology. Livingstone, New York, pp 167–196Google Scholar
  2. Bengzon ARA, Rasmussen T, Gloor P, Dussault J, Stephens M (1968) Prognostic factors in the surgical treatment of temporal lobe epileptics. Neurology 18: 717–731PubMedGoogle Scholar
  3. Engel J Jr, Driver MV, Falconer MA (1975) Electrophysiological correlates of pathology and surgical results in temporal lobe epilepsy. Brain 98: 129–156PubMedCrossRefGoogle Scholar
  4. Engel J Jr, Rausch R, Lieb JP, Kuhl DE, Crandall PH (1981) Correlation of criteria used for localizing epileptic foci in patients considered for surgical therapy of epilepsy. Ann Neurol 9: 215–224PubMedCrossRefGoogle Scholar
  5. Engel J Jr, Crandall PH, Rausch R (1983) The partial epilepsies. In: Rosenberg RN, Grossman RG, SchochetS, Heinz ER, Willis WD (eds) The clinical neurosciences, vol 2. Livingstone, New York, pp 1349–1380Google Scholar
  6. Engel J Jr, Sutherling WW, Cahan L, Crandall PH, Kuhl DE, Phelps ME (1984) The role of positron emission tomography in the surgical therapy of epilepsy. In: Porter RJ, Mattson RH, Ward AA, Dam M (eds) Advances in epileptology: XV th epilepsy international symposium. Raven, New York, pp 427–432Google Scholar
  7. Engel J Jr, Ebersole JS, Burchfiel JL, Gates JR, Gotman J, Homan RW, Ives JR, King DW, Sato S, Wilkus RJ (1985) Guidelines for long-term neurodiagnostic monitoring in epilepsy. J Clin Neurophysiol 2: 419–452Google Scholar
  8. Falconer MA (1976) Anterior temporal lobectomy for epilepsy. In: Rob C, Smith R (eds) Operative surgery, vol 14 2nd ed. Butterworths, London, pp 142–149Google Scholar
  9. Gloor P (1975) Contributions of electroencephalography and electrocorticography to the neurosurgical treatment of the epilepsies. In: Purpura DP, Penry JK, Walter RD (eds) Advances in neurology, vol 8. Neurosurgical management of the epilepsies. Raven, New York, pp 59–105Google Scholar
  10. Goldring S (1978) A method for surgical management of focal epilepsy, especially as it relates to children. J Neurosurg 49: 344–356PubMedCrossRefGoogle Scholar
  11. Gotman J, Ives JR, Gloor P (eds) (1985) Long-term monitoring in epilepsy. Electroencephalogy Clin Neurophysiol [Suppl 37], 444 ppGoogle Scholar
  12. Gumnit R (ed) (1987) Intensive neurodiagnostic monitoring. Advances in neurology, vol. 46, Raven, New York, 336 ppGoogle Scholar
  13. Lesser RP, Dinner DS, Luders H, Morris HH III (1984) Differential diagnosis and treatment of intractable seizures. Cleve Clin Q 51: 227–240PubMedGoogle Scholar
  14. Lieb JP, Engel J Jr, Brown WJ, Gevins AS, Crandall PH (1981a) Neuropathological findings following temporal lobectomy related to surface and deep EEG patterns. Epilepsia 22: 539–549PubMedCrossRefGoogle Scholar
  15. Lieb JP, Engel J Jr, Gevins AS, Crandall PH (1981b) Surface and deep EEG correlates of surgical outcome in temporal lobe epilepsy. Epilepsia 22: 515–538PubMedCrossRefGoogle Scholar
  16. Ojemann GA (1979) Individual variability in cortical localization of language. J Neurosurg 50: 164–169PubMedCrossRefGoogle Scholar
  17. Rand RW, Crandall PH, Walter RW (1964) Chronic stereotactic implantation of depth electrodes for psychomotor epilepsy. Acta Neurochir 11: 609–630CrossRefGoogle Scholar
  18. Talairach J, Bancaud J, Szikla G, et al. (1974) Approche nouvelle de la neurochirurgie de l’epilepsie. Methodologie stereotaxique et resultats therapeutiques. Neurochirurgie 20 [Suppl 1]: 1–240PubMedGoogle Scholar
  19. Wieser HG, Bancaud J, Talairach J, Bonis A, Szikla G (1979) Comparative value of spontaneous and chemically and electrically induced seizures in establishing the lateralization of temporal lobe seizures. Epilepsia 20: 47–59PubMedCrossRefGoogle Scholar
  20. Wyler AR, Ojemann GA, Lettich E, Ward AA Jr (1984) Subdural strip electrodes for localizing epileptogenic foci. J Neurosurg 60: 1195–1200PubMedCrossRefGoogle Scholar
  21. Yasargil MG, Teddy PJ, Roth P (1985) Selective amygdalo- hippocampectomy: operative anatomy and surgical technique. In: Symon L, Brihaye J, Guidetti B, Loew F, Miller JD, Nornes H, Pasztor E, Pertuiset B, Yasargil MG (eds) Advances and technical standards in neurosurgery, vol 12. Springer, Vienna, pp 93–123CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • J. EngelJr.
    • 1
  1. 1.Department of Neurology and Anatomy, UCLA School of Medicine, Reed Neurological Research CenterUniversity of CaliforniaLos AngelesUSA

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