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Pathological Changes Relevant for Seizure Generation

  • Y. Robitaille

Abstract

The type and extent of morphological changes which may be correlated with the electrophysiological phenomena characteristic of either the partial or generalized epilepsies cannot be dissociated from the molecular events underlying ictal activity. They must also reflect the abnormalities in neuronal-glial interrelationships which trigger or sustain neuronal seizure discharges. Neuronal pathological manifestations will first be explored, followed by relevant glial changes. The role of the blood brain barrier and other cell components will then be examined.

Keywords

Temporal Lobe Epilepsy Seizure Focus Focal Epilepsy Epileptic Focus Pipecolic Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • Y. Robitaille
    • 1
  1. 1.Montreal Neurological Institute and Departments of Neuropathology, Neurology, and NeurosurgeryMcGill UniversityMontréalCanada

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