Abstract
Genital warts (condylomata acuminata), the most common benign genital tumor in both sexes, have been considered for many centuries to be related to venereal diseases such as gonorrhea and syphilis (Oriel 1981). Until some 15 years ago condylomata acuminata were thought to be trivial lesions of little importance to the patient. There is no doubt today that these lesions are sexually transmissible and, in view of the striking increase in prevalence, they are recognized as one of the most important sexually transmitted diseases (STD). According to the Center for Disease Control (United States of America) genital warts are currently three times more common than genital herpes. In 1984 there were approximately 1 million new cases in the United States of America (Chuang et al. 1984). Human papillomaviruses (HPV) have been identified as the agents responsible for genital warts (Gissmann and zur Hausen 1980). The importance of HPV infection increased still further because of the recognized linkage between HPV and the development of malignant and premalignant conditions affecting the cervix, vagina, vulva, penis, and anus (zur Hausen 1982; Gissmann 1984) (Table 1). Another disease wherein HPV plays a significant role is epidermodysplasia verruciformis (EV). There are well-documented case reports on the malignant conversion of skin warts in this rare disorder.
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Gross, G. (1987). Lesions of the Male and Female External Genitalia Associated with Human Papillomaviruses. In: Syrjänen, K.J., Gissmann, L., Koss, L.G. (eds) Papillomaviruses and Human Disease. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71097-1_8
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