Intestinal Preservation of Small-Bowel Grafts by Vascular Washout and Cold Storage
The development of an effective method for preserving the small intestine during the interval between harvesting and implantation is a key factor to the success of future clinical small-bowel transplantation. In particular, a method of small-bowel preservation which allows for functional graft survival after ischemic intervals of up to 24 h should be devised. Such an interval is desirable to permit unhurried graft procurement from cadaveric donors and recipient preparation until the actual implantation is completed.
KeywordsCold Storage Vascular Anastomosis Entire Small Intestine Hypothermic Storage Accessory Graft
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- Hohenleitner FJ, Senior JR (1969) Metabolism of canine small intestine vascularly perfused in vitro. J App Physiol 26: 119–128Google Scholar
- Lee KKW, Schraut WH (1986) Structure and function of orthotopic small-bowel allografts in rats treated with cyclosporin A. Am J Surg (in press)Google Scholar
- Mozes MF, Finch WT, Reckard CR, Merkel FK, Cohen C (1985) Comparison of cold storage and machine perfusion of cadaver kidneys: A prospective, randomized study. Transplant Proc 17: 1474–1477Google Scholar
- Pitha J (1971) The fine structure of regenerating epithelium in the small intestine. Virchows Arch [Cell Pathol] 7: 314–341Google Scholar
- Robinson JWL, Antonioli JA, Mirkovitch V (1966) The intestinal response to ischemia. Naunyn-Schmiedebergs Arch Pharmacol 255: 178–191Google Scholar