Abstract
It is an important assumption in most studies on cerebrospinal fluid (csf) dynamics, that the pressure in the venous sinuses (Pss) does not change when the csf pressure (Pc) changes (Davson, Hollingsworth et al. 1970; Sullivan, Miller et al. 1979). By assuming a constant Pss, the changes in csf absorption with changes in Pc can be related to the Pc change alone without reference to the pressure in the recipient vessels, Pss. If however, the Pss changes in the same direction as a change in Pc, then csf outflow resistance will be overestimated if the no-change in Pss assumption is made. If Pss changes in the opposite direction to Pc then outflow resistance will be underestimated.
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References
Davson H, Hollingsworth G (1970) Segal MB: The mechanism of drainage of the cerebrospinal fluid. Brain 93: 665–678
Ekstedt J (1977) CSF hydrodynamic studies in man. I. Method of constant pressure infusion. J Neurol. Neurosurg Psych 40: 105: 119
Sullivan HG, Miller JD, Griffith RL III, et al. (1979) Bolus versus steady-state infusion for determination of CSF outflow resistance. Ann Neurol 5: 228–238
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© 1986 Springer-Verlag Berlin Heidelberg
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Love, J.A., Ekstedt, J., Fridén, H. (1986). Labile Sagittal Sinus Pressures in the Cat. In: Miller, J.D., Teasdale, G.M., Rowan, J.O., Galbraith, S.L., Mendelow, A.D. (eds) Intracranial Pressure VI. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70971-5_24
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DOI: https://doi.org/10.1007/978-3-642-70971-5_24
Publisher Name: Springer, Berlin, Heidelberg
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