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Regional Cerebral Blood Flow and Glucose Metabolism in Old Age and in Dementia Evaluated by PET

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Abstract

Function of neural tissue is closely linked to glucose consumption as the most important energy-supplying metabolic process. Therefore, regional disturbances as well as changes in functional activity can be detected with this metabolic variable. At the time being, only positron emission tomography (PET) affords regional and three-dimensional quantitation of glucose metabolism in the human brain, using measurements of the concentration of an injected radiolabeled glucose analogue in small volumes of tissue, and computer reconstruction of tomographic images showing the spatial tracer distribution. On those sections the individual anatomical structures of the brain are represented according to their metabolic activity.

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© 1986 Springer-Verlag Berlin Heidelberg

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Heiss, WD., Pawlik, G., Herholz, K., Wienhard, K. (1986). Regional Cerebral Blood Flow and Glucose Metabolism in Old Age and in Dementia Evaluated by PET. In: Häfner, H., Moschel, G., Sartorius, N. (eds) Mental Health in the Elderly. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70958-6_15

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  • DOI: https://doi.org/10.1007/978-3-642-70958-6_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-70960-9

  • Online ISBN: 978-3-642-70958-6

  • eBook Packages: Springer Book Archive

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