Abstract
Gastrointestinal cancers were one of the first groups of cancers to be extensively investigated with tumor-associated antigens [1–3]. During the last 20 years, carcinoembryonic antigen (CEA) has been established as the first clinically accepted tumor marker in this cancer group [4–5]. Recently, based on monoclonal antibody techniques, the position of CEA as the leading tumor marker in this cancer group has been seriously challenged by a new tumor-associated antigen, CA 19-9 [5–7]. The determinant group of the CA 19-9 antigen was found to be a modified (Lewis) blood group [8]. The monoclonal antibody originally established after immunization with colonic cancer cells was expected to be of high efficacy for this type of cancers [9]. Yet recent data gave evidence that this antigen might be highly useful in the diagnosis and follow-up of pancreatic carcinomas [10].
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© 1986 Springer-Verlag Berlin Heidelberg
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Staab, HJ. (1986). The Clinical Value of Tumor-Associated Proteins in Gastrointestinal Cancer. In: Winkler, C. (eds) Nuclear Medicine in Clinical Oncology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70947-0_39
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DOI: https://doi.org/10.1007/978-3-642-70947-0_39
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-16164-6
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