Production and Use of Positron-Emitting Test Substances for Tumor Diagnosis

  • W. H. Knapp
Conference paper


New therapeutic regimes like combinations of radio- or chemotherapy with hyperthermia have given rise to growing interest in methods for the in vivo assessment of tumor physiology and metabolism [1]. These methods usually require the use of radioactive compounds which undergo well-defined processes in the organism. Therefore, the attempt to monitor biologic properties of tumors necessitates considering organic radiopharmaceuticals and, in particular, positron emitters. This paper deals with the application of organic radioagents for the assessment of microcirculation and cellular integrity in tumors, and for therapeutic research.


Uptake Ratio Surrounding Normal Tissue Tumor Blood Flow Radioactive Compound Anhydrous Ether 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • W. H. Knapp
    • 1
    • 2
  1. 1.Deutsches KrebsforschungszentrumInstitut für NuklearmedizinHeidelberg 1Germany
  2. 2.Institut für NuklearmedizinHerzzentrum NRWBad OeynhausenGermany

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