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Metal Ions, Mitochondrial DNA and Aging

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Insect Aging

Abstract

It has been previously proposed that accumulation of errors in or damage to genetic material might represent the initiating event in cellular aging (Szilard 1959). The relationship between parental and filial life span (Falek et al. 1960), radiation-produced life span shortening (Lamson et al. 1959) and the inverse proportionality of the rate of germ-line mutation to the life span of various species (Failla 1960) have all been ascribed to genetic factors (Harman 1962).

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  1. Masonic Medical Research Laboratory, Utica, NY, USA

    H. R. Massie

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  1. Institut für Biologie I (Zoologie), Universität Freiburg, Albertstraße 21 a, D-7800, Freiburg, Germany

    Klaus-Günter Collatz

  2. Department of Biology, Southern Methodist University, Dallas, TX, 75275, USA

    Rajindar S. Sohal

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Massie, H.R. (1986). Metal Ions, Mitochondrial DNA and Aging. In: Collatz, KG., Sohal, R.S. (eds) Insect Aging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70853-4_11

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  • DOI: https://doi.org/10.1007/978-3-642-70853-4_11

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