Abstract
Photodynamic therapy (PDT) represents a new approach to treatment of a variety of malignant tumors in man and animals1. A nontoxic, photosensitizing drug with fluorescent properties, like hematoporphyrin derivative (HpD), is first injected systematically. After 2–3 days, this drug exhibits a higher retention in the cancer region than in the surrounding normal tissue. Subsequent irradiation with a proper optical wavelength, mainly red light around 630 nm, results in rapid necrosis of the neoplastic tissue.
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References
Y. Hayata, T. J. Dougherty, Eds.: Lasers and Hematoporphyrin Derivative in Cancer, Igaku-shoin, Tokyo (1983)
M. Shimamoto, S. Mashiko, S. Sato, H. Inaba, T. Kuwahara, Y. Taguchi, M. Kasai: J. Jpn. Soc. Laser Medicine, 5, 441 (1985) (in Japanese)
E. g., Y. R. Shen: The Principles of Nonlinear Optics, John Willy and Sons, New York (1984)
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© 1986 Springer-Verlag Berlin, Heidelberg
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Inaba, H. et al. (1986). Two-Photon Excited Fluorescence and Photochemical Effect of Hematoporphyrin on Cancer Cell Using a Nd: YAG Laser. In: Waidelich, W., Kiefhaber, P. (eds) Laser/Optoelectronics in Medicine/Laser/Optoelektronik in der Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70850-3_17
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DOI: https://doi.org/10.1007/978-3-642-70850-3_17
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-16018-2
Online ISBN: 978-3-642-70850-3
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