Abstract
Asbestos has been widely used in North America for insulation, corrosion resistance, material filling, and filtration. Of particular economic importance is chrysotile asbestos which is principally produced for western trading in Canada and Rhodesia. Interestingly, the first use of asbestos is thought to be 2,000 years ago when the Romans used asbestos cloth for wrapping their dead. Presently, attention is directed toward asbestos as a human toxicant and respiratory tract carcinogen. Although asbestos is a well-documented lung fibrogen and carcinogen, little is known about the mechanism of action.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Bonneau L and Pezerat H (1983) J Chim Phys 80: 275–280
Fisher GL and Bradley EW: US Patent 4, 220, 856 (September 1980)
Fisher GL, McNeill KL and Democko CJ (1983) In: Short-Term Bioassays in the Analysis of Complex Environmental Mixtures III, Waters, Sandhu, Lewtas, Claxton, Chernoff and Nesnow (eds) (Plenum) p257–268
Hall KY, Hart RW, Benirschky K and Walford RL (1984) Mech Aging and Devel 24: 163
Light WG, Wei ET (1980) In: The In Vitro Effects of Mineral Dusts (Brown RC, Chamberlain M, Davies R, Gormley IP (eds)), Acad Press, NY, p139–146
Monchaux G, Bignon J, Jaurand MC, Lafume J, Sebastien P, Masse R, Hirsch A and Goni J (1981) Carcinogenesis 2: 229
Mossman BT and Craighead JE (1975) I. Medium composition. Proc Soc Exp Biol Med 149: 127–133
Mossman BT and Landesman JM (1983) Chest 83: 50–51S
Robock K and Klosterkotter W (1973) Staub-Reinhalt Luft 33: 279–283
Stanton MF, Lagard M, Tegeris A, Miller E, Mag M and Graf E (1977) J Natl Cancer Inst 58: 587
Valentine R, Chang MJW, Hart RW, Finch GL and Fisher GL (1983) Environ Health Perspect 51: 357–368
Weitzman SA and Graceffa P (1984) Arch Biochem Biophys 228: 373–376
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1985 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Fisher, G.L., McNeill, K.L., Mossman, B.T., Marsh, J., McFarland, A.R., Hart, R.W. (1985). Investigations into the Mechanisms of Asbestos Toxicity. In: Beck, E.G., Bignon, J. (eds) In Vitro Effects of Mineral Dusts. NATO ASI Series, vol 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70630-1_4
Download citation
DOI: https://doi.org/10.1007/978-3-642-70630-1_4
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-70632-5
Online ISBN: 978-3-642-70630-1
eBook Packages: Springer Book Archive