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The Mechanism of Action of Ciclosporin: A Continuing Puzzle

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Ciclosporin in Autoimmune Diseases

Abstract

Ciclosporin (CyA) exerts a number of pharmacological effects (Fig. 1). Its most interesting action by far, however, consists of selectively modulating defined subpopulations of immunocompetent cells. CyA can therefore be considered as the first drug of a new generation of immunosuppressants which has substantially contributed to immunopharmacology.

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  1. Preclinical Research, Sandoz Ltd, 4002, Basle, Switzerland

    J. F. Borel & B. Ryffel

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  1. J. F. Borel
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  1. Pharmaceutical Department MPP / PAI, Journals and Monographs, Sandoz Ltd, CH-4002, Basle, Switzerland

    Rosemarie Schindler

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© 1985 Sandoz Ltd, Basle

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Borel, J.F., Ryffel, B. (1985). The Mechanism of Action of Ciclosporin: A Continuing Puzzle. In: Schindler, R. (eds) Ciclosporin in Autoimmune Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70607-3_4

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  • DOI: https://doi.org/10.1007/978-3-642-70607-3_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-70609-7

  • Online ISBN: 978-3-642-70607-3

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