Treatment of Noninfectious Inflammatory Disorders of the Eye with Ciclosporin

  • P. Le Hoang
  • M. Fontaine


Since November 1983, we have been conducting an open pilot study in which we have treated 31 patients with various ocular inflammatory disorders of noninfectious origin. Previous studies have already shown the effectiveness of ciclosporin in the management of intra-ocular inflammation (1–5).


Gamma Glutamyl Transferase Posterior Uveitis Open Pilot Study Gingival Hypertrophy Gamma Glutamyl Transferase Serum 
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  1. 1.
    Graham EM, Sanders MD, James DG, Hamblin A, Grochowska EK, Dumonde D (1985) Cyclosporin A in the treatment of posterior uveitis. Trans Ophthalmol Soc UK 104:146PubMedGoogle Scholar
  2. 2.
    Le Hoang P, Fontaine M, Khalaf A, de Kozak Y, Debre P, Aupetit B, Thillaye B, Nussenblatt RB (1984) Treatment of severe posterior uveitis with cyclosporine A: preliminary results in France. 1st International Symposium on Uveitis, Hanasaari, Espoo, Finland, 16th-19th May 1984Google Scholar
  3. 3.
    Le Hoang P, Fontaine M, Khalaf A, Travers C, Saraux H, Loscas G, Massin M, Bernard JA, Gaudric A, de Kozak Y, Nussenblatt RB: Traitement des uvites non infectieuses par un nouvel immunomodulateur, la cyclosporine A. Société d’Ophthalmologie de Paris, France (Communication du 18 février 1984). Bull Soc Ophthalmol Fr (in press)Google Scholar
  4. 4.
    Nussenblatt RB, Palestine AG, Rook AH, Scher I, Wacker WB, Gery I (1982) Treatment of intraocular inflammatory disease with Cyclosporin A. Lancet I:235Google Scholar
  5. 5.
    Nussenblatt RB, Palestine AG, Chan CC (1983) Cyclosporin A therapy in the treatment of intraocular inflammatory disease resistant to systemic corticosteroids and cytotoxic agnet. Am J Ophthalmol 96:275PubMedGoogle Scholar

Copyright information

© Sandoz Ltd, Basle 1985

Authors and Affiliations

  • P. Le Hoang
    • 1
  • M. Fontaine
    • 1
  1. 1.Service d’ophthalmologieHôpital la Pitié ParisFrance

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