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The Effect of Ciclosporin versus Azathioprine on the Course of Multiple Sclerosis; Design of a Long-term Follow-up Study and Side Effects

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Ciclosporin in Autoimmune Diseases

Abstract

The investigation which we are conducting in Hanover and Würzburg is a double-blind randomised stratified parallel group study comparing the effect of continuous CyA treatment with that of azathioprine treatment in patients with multiple sclerosis (ms). The primary object of this study is the progression of the disease, defined as the increase of clinical pathoneurological findings over a 2-year period.

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References

  1. Patzold U, Hecker H, Pocklington P (1982) Azathioprine in treatment of Multiple Sclerosis — Final results of a 41/2-year controlled study of its effectiveness covering 115 patients. J Neurol Sci 54:377–394

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Author information

Authors and Affiliations

  1. Neurologische Klinik und Poliklinik, Medizinische Hochschule Hannover, Germany

    U. Patzold, J. Haas & J. P. Malin

  2. Klinische Forschungsgruppe für Multiple Sklerose der Max-Planck-Gesellschaft an der Neurologischen Klinik, Universität Würzburg, Germany

    D. Dommasch & L. Kappos

  3. Abteilung Neurologie, Universität Göttingen, Germany

    Sigrid Poser

  4. Neurologische Klinik, Universität Würzburg, Germany

    P. Krauseneck

Authors
  1. U. Patzold
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  2. D. Dommasch
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  3. Sigrid Poser
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  4. L. Kappos
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  5. J. Haas
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  6. J. P. Malin
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  7. P. Krauseneck
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Editor information

Editors and Affiliations

  1. Pharmaceutical Department MPP / PAI, Journals and Monographs, Sandoz Ltd, CH-4002, Basle, Switzerland

    Rosemarie Schindler

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© 1985 Sandoz Ltd, Basle

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Patzold, U. et al. (1985). The Effect of Ciclosporin versus Azathioprine on the Course of Multiple Sclerosis; Design of a Long-term Follow-up Study and Side Effects. In: Schindler, R. (eds) Ciclosporin in Autoimmune Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70607-3_12

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  • DOI: https://doi.org/10.1007/978-3-642-70607-3_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-70609-7

  • Online ISBN: 978-3-642-70607-3

  • eBook Packages: Springer Book Archive

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