Abstract
We have used ciclosporin (CyA) since 1981 in the treatment of selected cases with severe autoimmune diseases. Our first patient suffered from life-threatening relapsing polychondritis. She had been treated with conventional immunosuppressive therapy without success, but after institution of CyA, a remarkable remission was seen [1]. Attempts to switch her over to chlorambucil met with failure. In four cases with inflammatory active rheumatoid arthritis we have observed remission of vasculitic ulcers and skin lesions during treatment with CyA but only modest effects on inflammatory synovial reactions. In accordance with others [2, 3] we have achieved excellent clinical effects of CyA in patients with Behçet’s disease (n = 3) and patients with chronic uveitis (n = 3).
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References
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Svenson K, Bohman S-O, Hällgren R: Renal interstitial fibrosis and vascular changes in patients with autoimmune diseases treated with cyclosporin. Submitted for publication
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© 1985 Sandoz Ltd, Basle
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Svenson, K., Bohman, SO., Hällgren, R. (1985). Clinical Effects and Renal Side Effects in Patients with Autoimmune Diseases Treated with Ciclosporin (CyA). In: Schindler, R. (eds) Ciclosporin in Autoimmune Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70607-3_10
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DOI: https://doi.org/10.1007/978-3-642-70607-3_10
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