The Functional Defect of Surgically Injured Endothelial Cells and Its Influence on Extra-Intracranial Arterial Bypass Surgery

  • R. Meyermann
  • J. Wickboldt
Conference paper
Part of the Advances in Neurosurgery book series (NEURO, volume 13)

Abstract

Different disturbances of the cerebrovascular system can be treated successfully by extra-intracranial arterial bypass (EIAB) surgery. Most of these disturbances are caused not by a localized nonpatent blood vessel but by a general disease of the circulatory system. This implies that the pathologically changed blood vessel causing the cerebral blood flow disturbances is not the only one exhibiting pathological changes. Thus it must be assumed that those extra- and intracranial arteries which come under consideration for EIAB surgery might be affected, too. This has been demonstrated in the case of the superficial temporal artery, which most often demonstrates a severe fibrosis of the tunica intima (3). However, these pathological changes do not prevent the use of this blood vessel for EIAB surgery.

Keywords

Peroxid Saccharose Ischemia Neurol Fibril 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Joris, I., Manjo, G.: Cell-to-cell herniae in the arterial wall. 1. The pathogenesis of vacuoles in the normal media. Am. J. Pathol. 87, 378–387 (1977)Google Scholar
  2. 2.
    Karnovsky, M.J.: The ultrastructural basis of capillary permeability studied with peroxidase as a tracer. J. Cell Biol. 35, 213–236 (1967)PubMedCrossRefGoogle Scholar
  3. 3.
    Kletter, G., Meyermann, R., Feigl, W., Sinzinger, H.: Importance of the histological structure of the superficial temporal artery for the function of extra-intracranial bypass. In: Schmiedek, P. (ed.) Microsurgery for stroke. Springer, New York 1977Google Scholar
  4. 4.
    Kreutzberg, G.W., Hager, H.: Electron microscopical demonstration of acid phosphatase activity in the central nervous system. Histochemie 6, 254–259 (1966)PubMedCrossRefGoogle Scholar
  5. 5.
    Mehdorn, H.M., Wiedemeyer, H., Reinhardt, V., Gerhard, L., Zais, E.: Histologische Veränderungen der A. temporalis superficialis and ihre Bedeutung für die extra-intrakranielle Bypass-Operation. Neurochirurgia 26, 181–186 (1983)PubMedGoogle Scholar
  6. 6.
    Meyermann, R., Ahyai, A., Kletter, G., Pini, C.: Ultrastructural control of small vessels following microsurgical intervention by tissue adhesion with fibrin. In: Peerless, S.J., McCormick, C.W. Microsurgery for cerebral ischemia, pp. 190–197. Springer, New York Heidelberg Berlin 1980CrossRefGoogle Scholar
  7. 7.
    Meyermann, R., Kletter, G.: Histologische und ultrastrukturelle Befunde nach extraintrakraniellen Gefäßanastomosen. In: Lechner, H., Ladurner, G. (eds.) Die zerebralen transitorisch-ischämischen Attacken. Hans Huber, Bern Stuttgart Wien 1979Google Scholar
  8. 8.
    Pott, G., Staubesand, J.: Lysosomen and lysosomale Enzyme in der Wand fehlbelasteter Arterien der Ratte. Res. Exp. Med. 170, 271–281 (1977)CrossRefGoogle Scholar
  9. 9.
    Reese, T.S., Karnovsky, M.J.: Fine structural localization of a blood brain barrier to exogenous peroxidase. J. Cell Biol. 34, 207–217 (1967)PubMedCrossRefGoogle Scholar
  10. 10.
    Webster, W.S., Bishop, S.P., Geer, J.C.: Experimental aortic intimal thickening. Am. J. Pathol. 76, 265–274 (1974)PubMedGoogle Scholar
  11. 11.
    Wilkinson, I.M.S.: The vertebral artery. Extracranial and intra-cranial structure. Arch. Neurol. 27, 392–396Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • R. Meyermann
    • 1
  • J. Wickboldt
    • 2
  1. 1.Klinische Forschungsgruppe für Multiple SkleroseMax-Planck-GesellschaftWürzburgGermany
  2. 2.Neurochirurgische AbteilungFachkrankenhaus Klinik SchildautalSeesen, HarzGermany

Personalised recommendations