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Copper and Inflammation

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Oncogenes and Human Cancer Blood Groups in Cancer Copper and Inflammation Human Insulin

Part of the book series: Progress in Clinical Biochemistry and Medicine ((PCBM,volume 2))

Abstract

Copper belongs to the biochemically active and essential transition metals. At present more than twenty different copper proteins are known. Their molecular properties and functional side is well characterized. In each of these proteins the copper is coordinated to the respective polypeptide side chains and is, in fact, the active centre. Copper exerts several distinct properties including the positive redox potential, the pronounced chelating activity and the extraordinary kinetic properties. Attributable to these properties this transition metal is preferentially active in electron transport reactions. Oxygen belongs to the preferred substrates. Very little is known on the biochemical reactivity of copper in inflammation. One of the major causes of inflammation is assigned to the action of excited oxygen species. Quite frequently, a rise of the copper concentration in serum up to a factor of four is observed in the course of inflammatory diseases. Extraneously administered copper has an antiinflammatory effect. We do not know whether or not the reactivity of copper must be exclusively seen in the biochemistry of oxygen. It is attempted to summarize the present thoughts and facts on the general biochemistry of both copper and inflammation. It will be attempted to correlate the biochemical properties of this most prominent transition metal with the biological aspects of inflammation.

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References

  1. Joachim, H.: Papyros Ebers, Berlin, Georg Reimer Verlag 1890

    Google Scholar 

  2. Plinius der Ältere, C. P.: Naturalis Historia, Liber XXXIV, Stuttgart, Teubner Verlag 1967

    Google Scholar 

  3. Rademaeher, J. G.: Rechtfertigung der von den Gelehrten mißkannten, verstandesrechten Erfahrungsheillehre der alten scheidekünstigen Geheimärzte und treue Mittheilung der Ergebnisse einer 25jährigen Erprobung dieser Lehre am Krankenbette, Berlin, Georg Reimer Verlag 1843

    Google Scholar 

  4. Kobert, R.: Dtsch. Med. Wochenstr.21, 5 (1895)

    Article  Google Scholar 

  5. Hart, E. B., Steinbock, H., Waddell, J., Elvehjem, C. A.: J. Biol. Chem.77, 797 (1928)

    CAS  Google Scholar 

  6. Basolo, F., Pearson, R. G.: Mechanisms of Inorganic Reactions, 2nd edition, New York, J. Wiley 1967

    Google Scholar 

  7. Lontie, R., Witters, R.: Inorganic Biochemistry (ed. Eichhorn, G.) p. 344, Amsterdam, Elsevier 1973

    Google Scholar 

  8. Weser, U.: Struct. Bonding17, 1 (1973)

    Article  CAS  Google Scholar 

  9. Fridovich, I.: Annu. Rev. Biochem.44, 147 (1975)

    Article  PubMed  CAS  Google Scholar 

  10. Fee, J. A .: Metal Ions in Biological Systems, Vol. 13 (ed. Sigel, H.) p. 259, New York, Marcel Dekker 1981

    Google Scholar 

  11. Büttner, G. R .: Inflammatory Diseases and Copper (ed. Sorenson, J. R. J.) p. 199, Clifton NJ, Humana Press 1982

    Chapter  Google Scholar 

  12. Harris, E. D., DiSilvestro, R. A., Balthrop, J. E.: ibid., p. 183

    Google Scholar 

  13. Opsahl, W.: J. Nutr.112, 708 (1982)

    PubMed  CAS  Google Scholar 

  14. Knowles, P. F., Lowe, D. J., Peters, J., Thorneley, R. N. F., Yadav, K. D. S.: NATO Adv. Study Inst. Ser., Ser. C100, 159 (1983)

    CAS  Google Scholar 

  15. Dooley, D. M., Golnik, K. C.: J. Biol. Chem.258, 4245 (1983)

    PubMed  CAS  Google Scholar 

  16. Eipper, B. A., Mains, R. E., Glembotski, C. C.: Proc. Natl. Acad. Sei. U.S.A.80, 5144 (1983)

    Article  CAS  Google Scholar 

  17. Lerch, K .: Metal Ions in Biological Systems, Vol. 13 (ed. Sigel, H.) p. 143, New York, Marcel Dekker 1981

    Google Scholar 

  18. Skotland, T., Fiatmark, T.: Eur. J. Biochem. 132, 111 (1983)

    Article  Google Scholar 

  19. Brunori, M., Antonini, E., Wilson, M. T.: Metal Ions in Biological Systems, Vol. 13 (ed. Sigel, H.) p. 187, New York, Marcel Dekker 1981

    Google Scholar 

  20. Kadenbach, B.: Angew. Chem.95, 273 (1983)

    Article  CAS  Google Scholar 

  21. Fee, J. A.: Struct. Bonding23, 1 (1975)

    Article  CAS  Google Scholar 

  22. Frieden, E .: Metal Ions in Biological Systems, Vol. 13 (ed. Sigel, H.) p. 117, New York, Marcel Dekker 1981

    Google Scholar 

  23. Goldstein, I. M., Charo, I. F.: Lymphokines 8, 373 (1983)

    CAS  Google Scholar 

  24. Lappin, A. G .: Metal Ions in Biological Systems, Vol. 13 (ed. Sigel, H.) p. 15, New York, Marcel Dekker 1981

    Google Scholar 

  25. Hartmann, H. J., Weser, U.: Biochim. Biophys. Acta491, 211 (1977)

    CAS  Google Scholar 

  26. Brady, F. O.: Trends Biochem. Sci.7, 143 (1982)

    Article  CAS  Google Scholar 

  27. Weser, U., Hartmann, H. J.: Copper Proteins and Copper Enzymes, Vol. III (ed. Lontie, R.) p. 151, Boca Raton, CRC Press 1984

    Google Scholar 

  28. Tainer, J. A., Getzoff, E. D., Richardson, J. S., Richardson, D. C.: 250 D: Cu, Zn-Superox- ide Dismutase Complete Atomic Coordinates (eds. Richardson, D. C., Richardson, J. S.) Brookhaven NY, Brookhaven Protein Structure Data Bank 1980

    Google Scholar 

  29. Malkin, R., Malmström, B. G.: Adv. Enzymol.33, 111 (1970)

    Google Scholar 

  30. Gray, H. B.: Adv. Inorg. Biochem.2, 1 (1980)

    Article  CAS  Google Scholar 

  31. Gray, H. B., Solomon, E. I.: Copper Proteins, Metal Ions in Biology, Vol. 3 (ed. Spiro, T. G.) p. 1, New York, John Wiley 1981

    Google Scholar 

  32. Solomon, E. I., Hare, J. W., Dooley, D. M., Dawson, J. H., Stephens, P. J., Gray, H. B.: J. Am. Chem. Soc.102, 168 (1980)

    Article  CAS  Google Scholar 

  33. Thompson, J. S., Marks, T. J., Ibers, J. A.: ibid.101, 4180 (1979)

    Article  CAS  Google Scholar 

  34. Co, M. S., Hodgson, K. O., Eccles, T. K., Lontie, R.: ibid.103, 984 (1981)

    Article  CAS  Google Scholar 

  35. Hahn, J. E., Co, M. S., Spira, D. J., Hodgson, K. O., Solomon, E. I.: Biochem. Biophys. Res. Commun.112, 737 (1983)

    Article  CAS  Google Scholar 

  36. Spira, D. J., Co, M. S., Solomon, E. I., Hodgson, K. O.: ibid.112, 746 (1983)

    Article  CAS  Google Scholar 

  37. Gubler, C. J., Lahey, M. E., Cartwright, G. E., Wintrobe, M.: J. Clin. Invest.32, 405 (1953)

    Article  PubMed  CAS  Google Scholar 

  38. Sternlieb, I., Morell, A. G., Tucker, W. D., Greene, M. W., Scheinberg, I. H.: ibid.40, 1834 (1961)

    Article  PubMed  CAS  Google Scholar 

  39. Evans, G. W.: Physiol. Rev.53, 535 (1973)

    PubMed  CAS  Google Scholar 

  40. Lau, S., Sarkar, B.: J. Biol. Chem.246, 5938 (1971)

    PubMed  CAS  Google Scholar 

  41. Earl, C. J., Moulton, M. J., Selverstone, B.: Am. J. Med.17, 205 (1954)

    Article  PubMed  CAS  Google Scholar 

  42. Neumann, P. Z., Sass-Kortsak, A.: J. Clin. Invest.46, 646 (1967)

    Article  PubMed  CAS  Google Scholar 

  43. May, P. M., Williams, D. R.: Metal Ions in Biological Systems, Vol. 12 (ed. Sigel, H.) p. 283, New York, Marcel Dekker 1981

    Google Scholar 

  44. Klug-Roth, D., Rabani, J.: J. Phys. Chem.80, 588 (1976)

    Article  CAS  Google Scholar 

  45. Yatsimirski, K. B., Vasilev, V. P.: Instability Constants of Complex Compounds, p. 149, Oxford, Pergamon Press 1960

    Google Scholar 

  46. Abbasi, S. A., Sharma, R. K.: J. Inorg. Nucl. Chem.43, 625 (1981)

    Article  CAS  Google Scholar 

  47. Weinstein, J., Bielski, B. H. J.: J. Am. Chem. Soc.102, 4916 (1980)

    Article  CAS  Google Scholar 

  48. Sarkar, B .: Metal Ions in Biological Systems, Vol. 12 (ed. Sigel, H.) p. 233, New York, Marcel Dekker 1981

    Google Scholar 

  49. Jackson, G. E., May, P. M., Wilhams, D. R.: FEBS Lett.90, 173 (1978)

    Article  PubMed  CAS  Google Scholar 

  50. Beam, A. G., Kunkel, H. G.: Proc. Soc. Exp. Biol.85, 44 (1954)

    Google Scholar 

  51. Stein, W. H., Moore, S.: J. Biol. Chem.211, 915 (1954)

    PubMed  CAS  Google Scholar 

  52. Felig, P.: Annu. Rev. Biochem.44, 933 (1975)

    Article  PubMed  CAS  Google Scholar 

  53. Sorenson, J. R. J.: Prog. Med. Chem.15, 211 (1978)

    Article  PubMed  CAS  Google Scholar 

  54. Niedermeier, W.: Ann. Rheum. Dis.24, 544 (1965)

    Article  PubMed  CAS  Google Scholar 

  55. Lorber, A., Cutler, L. S., Chang, C. C.: Arthritis Rheum.11, 65 (1968)

    Article  PubMed  CAS  Google Scholar 

  56. Kampschmidt, R. F.: J. Reticuloendothelial Soc.23, 287 (1978)

    CAS  Google Scholar 

  57. Koskelo, P., Kekki, M., Nikkila, E. A., Virkkunen, M.: Scand. J. Clin. Lab. Invest.19, 259 (1967)

    Article  CAS  Google Scholar 

  58. Hartmann, H. J., Morpurgo, L., Desideri, A., Rotilio, G., Weser, U.: FEBS Lett.152, 94 (1983)

    Article  PubMed  CAS  Google Scholar 

  59. Morpurgo, L., Hartmann, H. J., Desideri, A., Weser, U., Rotilio, G.: Biochem. J.211, 515 (1983)

    PubMed  CAS  Google Scholar 

  60. Hartmann, H. J., Gärtner, A., Weser, U.: Hoppe-Seyler’s Z. Physiol. Chem.365, 1355 (1984)

    Article  CAS  Google Scholar 

  61. Sass-Kortsak, A.: Adv. Clin. Chem.8, 1 (1965)

    Article  PubMed  CAS  Google Scholar 

  62. Neumann, P. Z., Silverberg, M.: Nature210, 414 (1966)

    Article  PubMed  CAS  Google Scholar 

  63. Harris, D. I. M., Sass-Kortsak, A.: J. Clin. Invest.46, 659 (1967)

    Article  PubMed  CAS  Google Scholar 

  64. Neumann, P. Z., Silverberg, M.: Nature213, 775 (1967)

    Article  PubMed  CAS  Google Scholar 

  65. Pickart, L., Freedman, J. H., Loker, W. J., Peisach, J., Perkins, C. M., Stenkamp, R. E., Weinstein, B.: ibid.288, 715 (1980)

    Article  PubMed  CAS  Google Scholar 

  66. Schmitt, R. C., Darwish, H. M., Cheney, J. C., Ettinger, M. J.: Am. J. Physiol.244, G183 (1983)

    PubMed  CAS  Google Scholar 

  67. Smith, B. S. W., Wright, H.: Biochim. Biophys. Acta307, 590 (1973)

    Article  CAS  Google Scholar 

  68. Marceau, N., Aspin, N.: Am. J. Physiol.222, 106 (1972)

    PubMed  CAS  Google Scholar 

  69. Hsieh, H. S., Frieden, E.: Biochem. Biophys. Res. Commun.67, 1326 (1975)

    Article  CAS  Google Scholar 

  70. Harris, E. D., DiSilvestro, R. A.: Proc. Soc. Exp. Biol. Med.166, 528 (1981)

    CAS  Google Scholar 

  71. Raju, K. S., Alessandri, G., Ziehe, M., Gullino, P. M.: J. Natl. Cancer Inst.69, 1183 (1982)

    PubMed  CAS  Google Scholar 

  72. Owen, C. A.: Proc. Soc. Exp. Biol. Med.149, 681 (1975)

    CAS  Google Scholar 

  73. Fenz, E.: Muench. Med. Wochenschr.41, 1101 (1951)

    Google Scholar 

  74. Forestier, J., Certonciny, A.: Presse Med.64, 884 (1946)

    Google Scholar 

  75. Hangarter, W. S .: Inflammatory Diseases and Copper (ed. Sorenson, J. R. J.) p. 439, Clifton NJ, Humana Press 1982

    Chapter  Google Scholar 

  76. Sorenson, J. R. J.: J. Med. Chem.19, 135 (1976)

    Article  PubMed  CAS  Google Scholar 

  77. Rainsford, K. D., Whitehouse, M. W.: J. Pharm. Pharmacol.28, 83 (1976)

    Article  PubMed  CAS  Google Scholar 

  78. Denko, C. W., Whitehouse, M. W.: J. Rheumatol.3, 54 (1976)

    PubMed  CAS  Google Scholar 

  79. Whitehouse, M. W., Walker, W. R.: Agents Actions8, 85 (1978)

    Article  PubMed  CAS  Google Scholar 

  80. Lewis, A. J.: ibid.8, 244 (1978)

    Article  PubMed  CAS  Google Scholar 

  81. Williams, D. A., Walz, D. T., Foye, W. O.: J. Pharm. Sci.65, 126 (1976)

    Article  PubMed  CAS  Google Scholar 

  82. Lewis, A. J., Smith, W. E., Brown, D. H.: Agents Actions Suppl.8, 327 (1981)

    PubMed  CAS  Google Scholar 

  83. Lewis, E. J., West, G. B.: ibid.8, 339 (1981)

    PubMed  CAS  Google Scholar 

  84. Perrin, D. D., Whitehouse, M. W.: ibid.8, 261 (1981)

    PubMed  CAS  Google Scholar 

  85. Walker, W. R., Beveridge, S. J., Whitehouse, M. W.: Agents Actions10, 38 (1980)

    Article  PubMed  CAS  Google Scholar 

  86. Beveridge, S. J., Walker, W. R., Whitehouse, M. W.: J. Pharm. Pharmacol.32, 425 (1980)

    Article  PubMed  CAS  Google Scholar 

  87. Dollwet, H. H. A., Schmidt, S. P., Seeman, R. E.: Inflammatory Diseases and Copper (ed. Sorenson, J. R. J.) p. 347, Clifton NJ, Humana Press 1982

    Chapter  Google Scholar 

  88. Thiery, M.: Contracept. Delivery Syst.4, 175 (1983)

    CAS  Google Scholar 

  89. Walker, W. R., Griffin, B. J.: Search7, 100 (1976)

    CAS  Google Scholar 

  90. Walker, W. R., Reeves, R. R., Brosnan, M., Coleman, G. D.: Bioinorg. Chem.7, 271 (1977)

    Article  PubMed  CAS  Google Scholar 

  91. Oyanagui, Y.: Biochem. Pharmacol.25, 1465 (1976)

    Article  PubMed  CAS  Google Scholar 

  92. McCord, J. M., Stokes, S. M., Wong, K.: Adv. Inflammation Res.1, 273 (1979)

    CAS  Google Scholar 

  93. Wolf, B .: Inflammatory Diseases and Copper (ed. Sorenson, J. R. J.) p. 453, Clifton NJ, Humana Press 1982

    Chapter  Google Scholar 

  94. Baret, A., Jadot, G., Valli, M., Bruguerolle, B., Puget, K., Michelson, A. M.: Oxy Radicals and Their Scavenger Systems, Volume II (ed. Cohen, G., Greenwald, R.A.) p. 274, New York NY, Elsevier 1983

    Google Scholar 

  95. Denko, C. W.: Agents Actions9, 333 (1979)

    Article  PubMed  CAS  Google Scholar 

  96. Milanino, R., Conforti, A., Fracasso, M. E., Franco, L., Leone, R., Passarella, A., Tarter, G., Velo, G. P.: ibid.9, 581 (1979)

    Article  PubMed  CAS  Google Scholar 

  97. Milanino, R., Velo, G. P.: Agents Actions Suppl.8, 209 (1981)

    PubMed  CAS  Google Scholar 

  98. Vane, J. R.: Angew. Chem.95, 782 (1983)

    Article  CAS  Google Scholar 

  99. Samuelsson, B.: Angew. Chem.95, 854 (1983)

    Article  CAS  Google Scholar 

  100. Bergström, S.: Angew. Chem.95, 865 (1983)

    Article  Google Scholar 

  101. Hammarström, S.: Annu. Rev. Biochem.52, 355 (1983)

    Article  PubMed  Google Scholar 

  102. Pinckard, R. N.: Monogr. Pathol.23, 38 (1982)

    PubMed  CAS  Google Scholar 

  103. Salin, M. L., McCord, J. M.: Superoxide and Superoxide Dismutases (eds. Michelson, A. M., McCord, J. M., Fridovich, I.) p. 257, New York, Academic Press 1977

    Google Scholar 

  104. Badwey, J. A., Karnovsky, M. L.: Annu. Rev. Biochem.49, 695 (1980)

    Article  PubMed  CAS  Google Scholar 

  105. Markert, M., Allaz, M. J., Frei, J.: FEBS Lett.113, 225 (1980)

    Article  PubMed  CAS  Google Scholar 

  106. Kuehl, F. A., Humes, J. L., Egan, R. W., Ham, E. A., Beveridge, G. C., van Arman, C. G.: Nature265, 170 (1977)

    Article  PubMed  CAS  Google Scholar 

  107. Singh, A.: Photochem. Photobiol.28, 429 (1978)

    Article  Google Scholar 

  108. Paschen, W., Weser, U.: Hoppe-Seyler Z. Physiol. Chem.356, 727 (1975)

    Article  CAS  Google Scholar 

  109. Janoff, A., Harvey, C.: Monogr. Pathol.23, 62 (1982)

    PubMed  CAS  Google Scholar 

  110. Vinegar, R., Schreiber, W., Hugo, R.: J. Pharmacol. Exp. Ther.166, 96 (1969)

    PubMed  CAS  Google Scholar 

  111. Bonta, I. L., Bult, H., Parnham, M. J., Vincent, J. E.: Agent Actions8, 98 (1978)

    Article  CAS  Google Scholar 

  112. Flower, R. J., Harvey, E. A., Kingston, W. P.: Br. J. Pharmacol.56, 229 (1976)

    PubMed  CAS  Google Scholar 

  113. DelMaestro, R. F., Björk, A., Arfors, K. E.: Microvasc. Res.22, 239 (1981)

    Article  CAS  Google Scholar 

  114. Bitter-Suermann, D.: Agents Actions Suppl.11, 159 (1982)

    PubMed  CAS  Google Scholar 

  115. Del Principe, D., Menichelli, A., Galli, E., Persiani, M., Perlini, M., D’Arcangelo, C., Businco, L., Rossi, P.: Pediatr. Res.16, 1000 (1982)

    Article  PubMed  Google Scholar 

  116. McCord, J. M., Petrone, W. F.: Lipid Peroxides in Biology and Medicine, Proc. Int. Conf. 1980 (ed. Yagi, K.) p. 123, New York, Academic Press 1982

    Google Scholar 

  117. Halliwell, B .: Copper Proteins and Copper Enzymes Vol.11 (ed. Lontie, R.) p. 63, Boca Raton CRC Press 1984

    Google Scholar 

  118. Brawn, K., Fridovich, I.: Acta Physiol. Scand. Suppl.492, 9 (1980)

    CAS  Google Scholar 

  119. McCord, J. M.: Science185, 529 (1974)

    Article  PubMed  CAS  Google Scholar 

  120. Lavelle, F., Michelson, A. M., Dimitrijevic, L.: Biochem. Biophys. Res. Commun.55, 350 (1973)

    Article  CAS  Google Scholar 

  121. Moody, C. S., Hassan, H. M.: Proc. Natl. Acad. Sei. U.S.A.79, 2855 (1982)

    Article  CAS  Google Scholar 

  122. Weser, U., Sellinger, K. H., Lengfelder, E., Werner, W., Strähle, J.: Biochim. Biophys. Acta631, 232 (1980)

    CAS  Google Scholar 

  123. Kellogg III, E. W., Fridovich, I.: J. Biol. Chem.250, 8812 (1975)

    PubMed  CAS  Google Scholar 

  124. Thomas, M. J., Mehl, K. S., Pryor, W. A.: Biochem. Biophys. Res. Commun.83, 927 (1978)

    Article  CAS  Google Scholar 

  125. Gutteridge, J. M. C.: ibid.77, 379 (1977)

    Article  CAS  Google Scholar 

  126. Lynch, R. E., Fridovich, I.: J. Biol. Chem.253, 1838 (1978)

    PubMed  CAS  Google Scholar 

  127. Goldberg, B., Stern, A.: Arch. Biochem. Biophys.178, 218 (1977)

    Article  PubMed  CAS  Google Scholar 

  128. Powanda, M. C.: Agents Actions Suppl.8, 121 (1981)

    PubMed  CAS  Google Scholar 

  129. Powanda, M. C .: Inflammatory Diseases and Copper (ed. Sorenson, J. R. J.) p. 31, Clifton NJ, Humana Press 1982

    Chapter  Google Scholar 

  130. Powanda, M. C.: Am. J. Clin. Nutr.30, 1254 (1977)

    PubMed  CAS  Google Scholar 

  131. Winter, C. A., Risley, E. A., Nuss, G. W.: J. Pharmacol. Exp. Ther.141, 369 (1963)

    CAS  Google Scholar 

  132. Meier, R., Schuler, W., Desaulles, P.: Experientia6, 469 (1950)

    Article  PubMed  CAS  Google Scholar 

  133. Aspinall, R. L., Cammarata, P. S.: Nature224, 1320 (1969)

    Article  PubMed  CAS  Google Scholar 

  134. Flower, R. J., Blackwell, G. P.: ibid.278, 456 (1979)

    Article  PubMed  CAS  Google Scholar 

  135. Hirata, F., Schiffmann, E., Venkatasubramanian, K., Salomon, D., Axelrod, J.: Proc. Natl. Acad. Sei. U.S.A.77, 2533 (1980)

    Article  CAS  Google Scholar 

  136. Shen, T. Y.: Handb. Exp. Pharmacol.50, 305 (1979)

    Article  CAS  Google Scholar 

  137. Walker, J. R., Dawson, W.: J. Pharm. Pharmacol.31, 778 (1979)

    Article  PubMed  CAS  Google Scholar 

  138. Issekutz, A. C.: Immunopharmacol.5, 183 (1983)

    Article  CAS  Google Scholar 

  139. Bailey, P. J.: Biochem. Pharmacol.32, 1213 (1982)

    Article  Google Scholar 

  140. Yamashita, T.: Inflammation6, 87 (1982)

    Article  PubMed  CAS  Google Scholar 

  141. Miyasaka, K.: Eur. J. Pharmacol.77, 229 (1982)

    Article  PubMed  CAS  Google Scholar 

  142. Rabani, J., Klug-Roth, D., Lilie, J.: J. Phys. Chem.77, 1169 (1973)

    Article  CAS  Google Scholar 

  143. Joester, K. E., Jung, G., Weber, U., Weser, U.: FEBS Lett.25, 25 (1972)

    Article  PubMed  CAS  Google Scholar 

  144. Brigelius, R., Spöttl, R., Bors, W., Lengfelder, E., Saran, M., Weser, U.: ibid.47, 72 (1974)

    Article  PubMed  CAS  Google Scholar 

  145. Brigelius, R., Hartmann, H. J., Bors, W., Saran, M., Lengfelder, E., Weser, U.: Hoppe- Seyler Z. Physiol. Chem.356, 739 (1975)

    Article  CAS  Google Scholar 

  146. Weser, U., Schubotz, L. M.: Agents Actions Suppl.8, 103 (1981)

    PubMed  CAS  Google Scholar 

  147. DeAlvare, L. R., Goda, K., Kimura, T.: Biochem. Biophys. Res. Commun.69, 687 (1976)

    Article  PubMed  CAS  Google Scholar 

  148. Younes, M., Lengfelder, E., Zienau, S., Weser, U.: ibid.81, 576 (1978)

    Article  PubMed  CAS  Google Scholar 

  149. O’Young, C. L., Lippard, S. J.: J. Am. Chem. Soc.102, 4920 (1980)

    Article  Google Scholar 

  150. Deuschle, U., Weser, U.: Inorg. Chim. Acta91, 237 (1984)

    Article  CAS  Google Scholar 

  151. Younes, M., Weser, U.: Biochem. Biophys. Res. Commun.78, 1247 (1977)

    Article  PubMed  CAS  Google Scholar 

  152. Lengfelder, E., Fuchs, C., Younes, M., Weser, U.: Biochim. Biophys. Acta567, 492 (1979)

    PubMed  CAS  Google Scholar 

  153. Pauling, L .: The Nature of the Chemical Bond, Ithaca NY, 1960

    Google Scholar 

  154. Van Niekerk, J. N., Schoening, F. R. L.: Acta Crystallogr.6, 227 (1953)

    Article  Google Scholar 

  155. Figgis, B. N., Martin, R. L.: J. Chem. Soc. 3837 (1956)

    Google Scholar 

  156. Suntsov, E. V., Ablov, A. V., Popovich, G. A., Kiosse, G. A.: Dokl. Akad. Nauk. S. S. R.179, 1352 (1968)

    CAS  Google Scholar 

  157. Yawney, D. B. W., Doedens, R. J.: Inorg. Chem.9, 1626 (1970)

    Article  CAS  Google Scholar 

  158. Wendel, A., Heidinger, S.: Res. Commun. Chem. Pathol. Pharmacol.28, 473 (1980)

    PubMed  CAS  Google Scholar 

  159. Amar, C., Vilkas, E., Foos, J.: J. Inorg. Biochem.17, 313 (1982)

    Article  CAS  Google Scholar 

  160. Marklund, S.: Acta Physiol. Scand. Suppl.492, 19 (1980)

    PubMed  CAS  Google Scholar 

  161. Oyanagui, Y.: Biochem. Pharmacol.19, 135 (1976)

    Google Scholar 

  162. Sorenson, J. R. J.: Inflammation1, 317 (1976)

    Article  CAS  Google Scholar 

  163. Cammack, R.: Biochem. Biophys. Res. Commun.54, 548 (1973)

    Article  PubMed  CAS  Google Scholar 

  164. Symonyan, M. A., Nalbandyan, R. M.: Biochim. Biophys. Acta446, 432 (1976)

    PubMed  CAS  Google Scholar 

  165. Rotilio, G., Bray, R. C., Fielden, E. M.: ibid.268, 605 (1972)

    PubMed  CAS  Google Scholar 

  166. Klug, D., Rabani, J., Fridovich, I.: J. Biol. Chem.247, 4839 (1973)

    Google Scholar 

  167. Klug-Roth, D., Fridovich, I., Rabani, J.: J. Am. Chem. Soc.95, 2786 (1972)

    Article  Google Scholar 

  168. Bannister, J. V., Bannister, W. H., Bray, R. C., Fielden, E. M., Roberts, P. B., Rotilio, G.: FEBS Lett.32, 303 (1973)

    Article  PubMed  CAS  Google Scholar 

  169. Pick, M., Rabani, J., Yost, F., Fridovich, I.: J. Am. Chem. Soc.96, 7329 (1974)

    Article  PubMed  CAS  Google Scholar 

  170. Lavelle, F., McAdam, M. E., Fielden, E. M., Roberts, P. B., Puget, K., Michelson, A. M.: Biochem. J.161, 3 (1977)

    PubMed  CAS  Google Scholar 

  171. Bohnenkamp, W., Weser, U.: Biochim. Biophys. Acta444, 396 (1976)

    PubMed  CAS  Google Scholar 

  172. Bettger, W. J., Savage, J. E., O’Dell, B. L.: Nutr. Rep. Int.19, 893 (1979)

    CAS  Google Scholar 

  173. Massie, H. R., Aiello, V. R., Iodice, A. A.: Mech. Ageing Dev.10, 93 (1979)

    Article  PubMed  CAS  Google Scholar 

  174. Gemsa, D., Leser, H. G., Seitz, M., Debatin, M., Bärlin, E., Deimann, W., Kramer, W.: Agents Actions Suppl.11, 93 (1982)

    PubMed  CAS  Google Scholar 

  175. Bonta, I. L., Parnham, I. J.: Biochem. Pharmacol.27, 1611 (1978)

    Article  PubMed  CAS  Google Scholar 

  176. Lee, R. E., Lands, W. E. M.: Biochim. Biophys. Acta260, 203 (1972)

    PubMed  CAS  Google Scholar 

  177. Maddox, I. S.: ibid.306, 74 (1973)

    PubMed  CAS  Google Scholar 

  178. Vargaftig, B. B., Tränier, Y., Chignard, M.: Eur. J. Pharmacol.33, 19 (1975)

    Article  PubMed  CAS  Google Scholar 

  179. Boyle, E., Freeman, P. C., Goudie, A. C., Mangan, F. R., Thomson, M.: J. Pharm. Pharmacol.28, 865 (1976)

    Article  PubMed  CAS  Google Scholar 

  180. Letellier, P. R., Smith, W. L., Lands, W. E. M.: Prostaglandins4, 837 (1973)

    Article  PubMed  CAS  Google Scholar 

  181. Prohaska, J. R., Lukasewycz, O. A.: Science213, 559 (1981)

    Article  PubMed  CAS  Google Scholar 

  182. Vyas, D., Chandra, R. K.: Nutr. Res.3, 343 (1983)

    Article  CAS  Google Scholar 

  183. Lukasewycz, O. A., Prohaska, J. R.: ibid.3, 335 (1983)

    Article  CAS  Google Scholar 

  184. Rigas, D. A., Eqinitis-Rigas, C., Head, C.: Biochem. Biophys. Res. Commun.88, 373 (1979)

    Article  PubMed  CAS  Google Scholar 

  185. Lipsky, P. E., Ziff, M.: J. Immunol.120, 1006 (1978)

    PubMed  CAS  Google Scholar 

  186. Brown, T. M., Bailey, J. S., Iden, I.I., Clark, H. W.: Inflammatory Diseases and Copper (ed. Sorenson, J. R. J.) p. 391, Clifton NJ, Humana Press 1982

    Chapter  Google Scholar 

  187. Van der Goot, H., Pijper, P. J., Smit, H.: ibid., p. 409

    Google Scholar 

  188. Sorenson, J. R. J.: ibid., p. 289

    Google Scholar 

  189. Harris, E. D.: Proc. Natl. Acad. Sei. U.S.A.73, 371 (1976)

    Article  CAS  Google Scholar 

  190. Ziehe, M., Jones, J., Gullino, P. M.: J. Natl. Cancer Inst.69, 475 (1982)

    Google Scholar 

  191. Alessandri, G., Raju, K., Gullino, P. M.: Cancer Res.43, 1790 (1983)

    PubMed  CAS  Google Scholar 

  192. McAuslan, B. R., Reilly, W.: Exp. Cell Res.130, 147 (1980)

    Article  PubMed  CAS  Google Scholar 

  193. Velo, G., Franco, L., Conforti, A., Milanino, R.: Inflammatory Diseases and Copper (ed. Sorenson, J. R. J.) p. 329, Clifton NJ, Humana Press 1982

    Google Scholar 

  194. Klevay, L. M.: ibid., p. 123

    Google Scholar 

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  1. Anorganische Biochemie, Physiologisch-chemisches Institut, Universität Tübingen, Hoppe-Seyler-Str. 1, 7400, Tübingen 1, Germany

    Ulrich Deuschle & Ulrich Weser

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  1. Ulrich Deuschle
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Deuschle, U., Weser, U. (1985). Copper and Inflammation. In: Oncogenes and Human Cancer Blood Groups in Cancer Copper and Inflammation Human Insulin. Progress in Clinical Biochemistry and Medicine, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70570-0_3

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  • DOI: https://doi.org/10.1007/978-3-642-70570-0_3

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