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Verteilungsmessungen von Zink und Cadmium im Hodengewebe bei Patienten mit Prostatakarzinomen verschiedener histologischer Differenzierung im Vergleich zu normalen Hoden

  • A. Feustel
  • R. Wennrich
  • H. Dittrich
Conference paper

Zusammenfassung

In Zellfraktionen von Hoden- und Nebenhodengewebe bei 19 Patienten mit Prostatakarzinomen verschiedener histologischer Differenzierung im Vergleich zu normalen Hoden wurden Zink und Cadmium mit Hilfe der flammenlosen AAS gemessen. Deutliche Unterschiede fanden sich in den Kernfraktionen für Zn und in den Mitochondrienfraktionen für Cd bei unterschiedlicher Histologie der Prostata. Verteilungsanalytische Untersuchungen von Zn in Gewebsschnitten gleicher Patientenauswahl ergab die höchste Zink-Konzentration im Kernepithel. Im Gegensatz zu Normalproben war im Interstitium des Hodens bei Prostatakarzinomen kein Zn nachweisbar.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • A. Feustel
    • 1
  • R. Wennrich
  • H. Dittrich
  1. 1.Urologische Abteilung, FE Krankenhaus, Sektion Chemie und Sektion TVKarl-Marx-UniversitätLeipzig-MarkkleebergDeutschland

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