Skip to main content
SpringerLink
Log in
Book cover

Ion Measurements in Physiology and Medicine pp 1–5Cite as

Ion Transport in Asymmetric Artificial Membranes Mediated by Neutral Carriers

  • Chapter

Abstract

Valuable information on the selectivity behavior and the response mechanisms of analytically relevant neutral carrier membrane electrodes has been obtained from ion transport studies performed on the corresponding cation-selective membranes [9,10,15,16]. In electrodialysis experiments, the permeation of cations was induced by a transmembrane potential gradient, whereas in zero current countertransport systems, cations were driven by an oppositely directed flow of hydrogen ions, as induced by a pH gradient. The selectivity of ion transport was usually found to correlate with the potentiometric ion selectivity of the corresponding membrane electrodes [9, 10, 15, 16]. So far, virtually all experiments have concentrated on homogeneous PVC membranes.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Apell H-J, Bamberg F, Alpes H, Läuger P (1977) Formation of ion channels by a negatively charged analog of gramicidin A. J Membr Biol 31:171–188

    Article  PubMed  CAS  Google Scholar 

  2. Deutsch DH (1981) Can the second law of thermodynamics be circumvented. Am Lab 13 (5): 54–65

    CAS  Google Scholar 

  3. Fiedler U (1977) Influence of the dielectric constant of the medium on the selectivities of neutral carrier ligands in electrode membranes. Anal Chim Acta 89:111–118

    Article  CAS  Google Scholar 

  4. Flagg-Newton JL, Loewenstein WR (1980) Asymmetrically permeable membrane channels in cell junction. Science 207: 771–773

    Article  PubMed  CAS  Google Scholar 

  5. Greco FA (1983) On the 2nd law of thermodynamics: a summary of the replies to Deutsch’s article. Int Lab 13 (1): 38–47

    Google Scholar 

  6. Ion transport across biological membranes and its control (1983) International workshop, Maria Laach, Germany, 25–27 Sept 1983

    Google Scholar 

  7. Köhne W, Deuticke B (1983) Incorporation of band 3 protein into lipid vesicles: influence of the phospholipid on anion transport. In: International Workshop, Maria Laach, Germany, 25–27 Sept 1983, pp 18–19

    Google Scholar 

  8. Krämer R (1983) The reconstituted ADP/ATP-carrier from mitochondria: functional and structural aspects of its two states of orientation. In: International Workshop, Maria Laach, Germany, 25–27 Sept 1983, pp 20–21

    Google Scholar 

  9. Morf WE (1981) The principles of ion-selective electrodes and of membrane transport. Akademiai Kiadö, Budapest; Elsevier, Amsterdam

    Google Scholar 

  10. Morf WE, Wuhrmann P, Simon W (1976) Transport properties of neutral carrier ion selective membranes. Anal Chem 48:1031–1039

    Article  CAS  Google Scholar 

  11. Morf WE, Ammann D, Bissig R, Pretsch E, Simon W (1979) Cation selectivity of neutral macro- cyclic and nonmacrocyclic complexing agents in membranes. In: Izatt RM, Christensen JJ (eds) Progress in macrocyclic chemistry, vol. 1. Wiley, New York, pp 1–61

    Google Scholar 

  12. Morf WE, Ruprecht H, Oggenfuss P, Simon W (1985) Ion transport in asymmetric artificial membranes mediated by neutral carriers. (In preparation)

    Google Scholar 

  13. Schwarz W, Grygorcyk R (1983) Patch-clamp analysis of Ca2+-activated K+ channels in the membranes of human erythrocytes. In: International Workshop, Maria Laach, Germany, 25–27 Sept 1983, pp 36–37

    Google Scholar 

  14. Simon W, Morf WE, Meier PC (1973) Specificity for alkali and alkaline earth cations of synthetic and natural organic complexing agents in membranes. In: Dunitz JD et al. (eds) Alkali metal complexes with organic ligands. Springer, Berlin Heidelberg New York, pp 113–160 (Structure and bonding, vol 16)

    Chapter  Google Scholar 

  15. Simon W, Morf WE, Pretsch E, Wuhrmann P (1975) Synthetic neutral ionophores for Ca2+ and their transport properties in bulk membranes. In: Carafoli E, Clementi F, Drabikowski W, Margreth A (eds) Calcium transport in contraction and secretion. North-Holland, Amsterdam, pp15–23

    Google Scholar 

  16. Thoma AP, Viviani-Nauer A, Arvanitis S, Morf WE, Simon W (1977) Mechanism of neutral carrier mediated ion transport through ion-selective bulk membranes. Anal Chem 49:1567–1572

    Article  CAS  Google Scholar 

  17. Vuilleumier P, Gazzotti P, Carafoli E, Simon W (1977) The translocation of Ca2+ across phospholipid bilayers induced by a synthetic neutral Ca2+-ionophore. Biochim Biophys Acta 467: 12–18

    Article  PubMed  CAS  Google Scholar 

Download references

Authors
  1. W. E. Morf
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. H. Ruprecht
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. P. Oggenfuss
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. W. Simon
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Institut för Physiologie und Kardiologie, Waldstr. 6, D-8520, Erlangen, Germany

    Manfred Kessler , David Keith Harrison  & Jens Höper ,  & 

  2. Dept. of Chemistry, University of North Carolina, Chapel Hill, NC, 27514, USA

    R. P. Buck

  3. Dept. of Physiology, School of Medicine, The Center for Health Science, University of California, Los Angeles, California, 90024, USA

    G. Eisenman

  4. Biosensors Inc., PO Box 640, Chester, New Jersey, 07930, USA

    J. Hill

  5. Faculty of Medicine, American Univ. of Beirut, Beirut, Lebanon

    R. N. Khuri

  6. Direktor des Max-Planck-Instituts für Systemphysiologie, Rheinlanddamm 201, 4600, Dortmund 1, Germany

    D. W. Lübbers

  7. Medical Center, Dept. of Physiology and Biophysics, New York University, 550 First Avenue, New York, NY, 10016, USA

    C. Nicholson

  8. Laboratorium für Organische Chemie, Universitätsstr. 16, 6000, Frankfurt M. 70, Germany

    W. Simon

  9. The Middlesex Hospital, Mortimer St., London W N, 8AA, England

    T. Treasure

  10. Institute of Medical Physiology, Dept. A, University of Copenhagen, DK-2200, Copenhagen N, Denmark

    T. Zeuthen

Rights and permissions

Reprints and permissions

Copyright information

© 1985 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Morf, W.E., Ruprecht, H., Oggenfuss, P., Simon, W. (1985). Ion Transport in Asymmetric Artificial Membranes Mediated by Neutral Carriers. In: Kessler, M., et al. Ion Measurements in Physiology and Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70518-2_1

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-70518-2_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-15468-6

  • Online ISBN: 978-3-642-70518-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation