Skip to main content
SpringerLink
Log in

Rhesus Incompatibility and Nonimmunologic Hydrops Fetalis

  • Chapter
Ultrasound Diagnosis in Obstetrics and Gynecology

  • 193 Accesses

Abstract

Rh incompatibility provides a good example of how a disease process can be elucidated and to some extent controlled through interdisciplinary cooperation — in this case between obstetricians, pediatricians, and serologists. Within a period of 30 years it has been possible to explain the pathogenesis of this disorder, develop reliable diagnostic methods, and find effective therapeutic measures.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Asensio SH, Figueroa-Longo JG, Pelegrina IA (1966) Intrauterine exchange transfusion. Am J Obstet Gynecol 95: 1128

    Google Scholar 

  • Berkowitz RL, Hobbins JC (1981) Intrauterine transfusion utilizing ultrasound. Obstet Gynecol 57: 33

    PubMed  CAS  Google Scholar 

  • Bierme SJ, Blanc M, Abbal M, Fournie A (1979) Oral Rh-treatment for severely immunised mothers. Lancet 1: 604

    Article  PubMed  CAS  Google Scholar 

  • Bowman JM (1975) Rh erythroblastosis 1975. Semin Hematol 12: 189

    PubMed  CAS  Google Scholar 

  • Bowman JM (1978) The management of Rh-isoimmunization. Obstet Gynecol 52: 1

    PubMed  CAS  Google Scholar 

  • Bowman JM (1984) Rhesus haemolytic disease. In: Wald N (ed) Antenatal and neonatal screening. Oxford University Press, Oxford New York Tokyo, p 314

    Google Scholar 

  • Bowman JM, Manning FA (1983) Intrauterine fetal transfusions: Winnipeg 1982. Obstet Gynecol 61: 203

    PubMed  CAS  Google Scholar 

  • Charles AG, Blumenthal LS (1982) Promethazine hydrochloride therapy in severely Rh-sensitized pregnancies. Obstet Gynecol 60: 627

    PubMed  CAS  Google Scholar 

  • Clewell WH, Dunne MG, Johnson ML, Bowes WA (1981) Fetal transfusion with real time ultrasound guidance. Obstet Gynecol 57: 516

    PubMed  CAS  Google Scholar 

  • Cooperberg PL, Carpenter CW (1977) Ultrasound as an aid in intrauterine transfusion. Am J Obstet Gynecol 128: 239

    PubMed  CAS  Google Scholar 

  • De Vore GR, Donnerstein RL, Kleinman CS, Piatt LD, Hobbins JC (1982) Fetal echocardiography. II. The diagnosis and significance of a pericardial effusion in the fetus using real-time-directed M-mode ultrasound. Am J Obstet Gynecol 144: 693

    Google Scholar 

  • Dewhurst CJ, Beazly JM, Campbell S (1972) Assessment of fetal maturity and dysmaturity. Am J Obstet Gynecol 113: 141

    PubMed  CAS  Google Scholar 

  • Finn R, Clarke CA, Donohoe WTA, Connel RB, Sheppard PM, Lehane D, Kulke W (1961) Experimental studies on the prevention of Rh hemolytic disease. Br Med J 1: 1486

    Article  PubMed  CAS  Google Scholar 

  • Freda VJ, Adamsons K (1964) Exchange transfusion in utero. Am J Obstet Gynecol 89: 817

    PubMed  CAS  Google Scholar 

  • Freda VJ, Gorman JG, Pollack W (1964) Successful prevention of experimental Rh sensitization in man with an anti-Rh gamma 2 — globulin antibody preparation: A preliminary report. Transfusion 4: 26

    Article  PubMed  CAS  Google Scholar 

  • Frigoletto FD, Umansky I, Birnholz J, Acker D, Easterday CL, Harris GBC, Griscom NT (1981) Intrauterine fetal transfusion in 365 fetuses during fifteen years. Am J Obstet Gynecol 139: 781

    PubMed  Google Scholar 

  • Hamilton EG (1977) Intrauterine transfusion. Safeguard or peril? Obstet Gynecol 50: 255

    PubMed  CAS  Google Scholar 

  • Hansmann M, Lang N (1972) Intrauterine Transfusion unter Ultraschallkontrolle. Klin Wochenschr 50: 930

    Article  PubMed  CAS  Google Scholar 

  • Hansmann M, Paulussen F, Weiβ H, Niesen M, Lang N, Plotz E-J (1980) Intrauterine Transfusion unter Real-Time-Ultraschall-Kontrolle. In: Hinselmann M, Anliker M, Meudt R (eds) Ultrasehalldiagnostik in der Medizin. Thieme, Stuttgart New York, S 159

    Google Scholar 

  • Hardyment AF, Salvador HS, Towell ME, Carpenter CW, Jan FE, Tingle AJ (1979) Follow-up of intrauterine transfused surviving children. Am J Obstet Gynecol 133: 235

    PubMed  CAS  Google Scholar 

  • Harman CR, Manning FA, Bowman JM, Lange IR (1983) Severe Rh disease — Poor outcome is not inevitable. Am J Obstet Gynecol 145: 823

    PubMed  CAS  Google Scholar 

  • Hauth JC, Brekken AL, Pollack W (1981) Plasmapheresis as am adjunct to management of Rh isoimmunization. Obstet Gynecol 57: 132

    PubMed  CAS  Google Scholar 

  • Hobbins JC, Davis ED, Webster J (1976) A new technique utilizing ultrasound to aid in intrauterine transfusion. J Clin Ultrasound 4: 135

    Article  PubMed  CAS  Google Scholar 

  • Holzgreve W, Hansmann M (1984) Erfahrungen mit der „Free hand needle” — Technik bei 3,215 Amniozentesen im II. Trimenon zur pranatalen Diagnostik. Gynakologe 17: 77

    Google Scholar 

  • Knobbe T, Meier P, Wenar C, Cordero L (1979) Psychological development of children who received intrauterine transfusion. Am J Obstet Gynecol 133: 877

    PubMed  CAS  Google Scholar 

  • Kopecky P (1971) Zur Diagnostik und Therapie der Rhesus-Inkompatibilitat und Untersuchungen zum fetalen Bilirubin-Metabolismus. Habilitationsschrift, RWTH Aachen

    Google Scholar 

  • Kowalewski S, Kochs G, Kartheiser C, Hansmann M (1981) Untersuchungen zur Spatprognose von Kindern mit M. haemolyticus neonatorum (Rh) nach intrauterinen Transfusionen. 77. Tagung der Dtsch Ges Kinderheilk, Diisseldorf, 20.-23. 09. 1981

    Google Scholar 

  • Kwi NK, High NK (1974) A simple technique of intrauterine transfusion of fetus in University Hospital. Kuala Lumpur. Med J Malaysia 28: 287

    Google Scholar 

  • Landsteiner K, Wiener AS (1940) An agglutinable factor in human blood recognized by immune sera for rhesus blood. Proc Soc Exp Biol Med 43: 223

    CAS  Google Scholar 

  • Larkin RM, Knochel JQ, Lee TG (1982) Intrauterine transfusions: New techniques and results. Clin Obstet Gynecol 25: 303

    Google Scholar 

  • Levine P, Stetson R (1939) An unusual case of intragroup agglutination. JAMA 113: 126

    Google Scholar 

  • Levine P, Katzin EM, Burnham L (1941) Isoimmunization in pregnancy: its possible bearing on the etiology of erythroblastosis fetalis. JAMA 116: 825

    Google Scholar 

  • Liley AW (1961) Liquor amnü analysis in the management of pregnancy complicated by rhesus sensitization. Am J Obstet Gynecol 82: 1359

    PubMed  CAS  Google Scholar 

  • Mast H (1969) Morbus haemolyticus neonatorum. Z Geburtshilfe 170 (Beilageheft)

    Google Scholar 

  • Parkman R, Mosier D, Umansky I, Cochran W, Carpenter CB, Rosen FS (1974) Graft-versus-host disease after intrauterine and exchange transfusions for hemolytic disease of the newborn. N Engl J Med 290: 359

    Article  PubMed  CAS  Google Scholar 

  • Peddle LJ, Campbell EM (1968) Radiation of the fetus in intrauterine transfusion. Am J Obstet Gynecol 100: 366

    PubMed  CAS  Google Scholar 

  • Preisler O, Schneider J (1964) Versuche der Sensibilisierung Rh-negativen Frauen durch antikorperhaltige Seren zu verhindern. Geburtshilfe Frauenheilkd 24: 124

    PubMed  CAS  Google Scholar 

  • Queenan JT, Wyatt RH (1965) Intrauterine transfusion of fetus for severe erythroblastosis fetalis. Am J Obstet Gynecol 92: 375

    PubMed  CAS  Google Scholar 

  • Queenan JT, Anderson GG, Mead PB (1966) Intrauterine transfusion by the multiple needle technique. JAMA 196: 664

    Article  PubMed  CAS  Google Scholar 

  • Rodeck CH, Nicolaides KH (1984) Anwendung der Fetoskopie bei fetaler Therapie. Gynakologe 17: 52

    PubMed  CAS  Google Scholar 

  • Rodeck CH, Holman CA, Karnicki J, Kemp JR, Whitmore DN, Austin MA (1981) Direct intravascular fetal blood transfusion by fetoscopy in severe rhesus isoimmunisation. Lancet 1: 625

    Article  PubMed  CAS  Google Scholar 

  • Schneider J, Maas DHA (1978) Rhesuserythroblastose. Klin Frauenheilkd 111:164/1 (Erganzung 1978)

    Google Scholar 

  • Seelen J, Kessel, Hiam V, Eskes T, Leusden H v, Been K, Evers J, Genet D v, Peeters L, Velden W, Zonderland F vd (1966) A new method of exchange transfusion in utero. Am J Obstet Gynecol 95: 872

    Google Scholar 

  • White CA, Goplerud CP, Kisker CT, Stehbens JA, Kitchell M, Taylor JC (1978) Intrauterine fetal transfusion, 1965-1976, with an assessment of the surviving children. Am J Obstet Gynecol 130: 933

    PubMed  CAS  Google Scholar 

  • Whitfield CR, Thompson W, Armstrong M, Reid McC (1972) Intrauterine fetal transfusion for severe rhesus haemolytic disease. Br J Obstet Gynaecol 79: 931

    Article  CAS  Google Scholar 

Diagnosis and Treatment

  • Andersen HM, Drew JH, Beischer NA, Hutchison AA, Fortune DW (1983) Non-immune hydrops fetalis: Changing contribution to perinatal mortality. Br J Obstet Gynaecol 90: 636

    Google Scholar 

  • Chervenak FA, Isaacson G, Blakemore KJ, Breg WR, Hobbins JC, Berkowitz RL, Tortora M, Mayden K, Mahoney MJ (1983) Fetal cystic hygroma. Cause and natural history. N Engl J Med 309: 822

    Google Scholar 

  • Clausen U, Hansmann M (1984) Die „Pipettenmethode” zur schnellen Karyotypisierung bei sonographischen Verdachtskriterien fur eine Chromosomenanomalie. Gynakologe 17: 33

    Google Scholar 

  • Daffos F, Capella-Pavlovsky M, Forestier F (1983) Fetal blood sampling via the umbilical cord using a needle guided by ultrasound: Report of 66 cases. Prenat Diagn 3: 271

    Article  PubMed  CAS  Google Scholar 

  • Davis CL (1982) Diagnosis and management of nonimmune hydrops fetalis. J Reprod Med 27: 594

    PubMed  CAS  Google Scholar 

  • DeVore GR, Donnerstein RL, Kleinmann CS, Piatt LD, Hobbins JC (1982) Fetal echocardiography. II. The diagnosis and significance of a pericardial effusion in the fetus using real-time-directed M-mode ultrasound. Am J Obstet Gynecol 144: 693

    Google Scholar 

  • DeVore GR, Siassi B, Piatt LD (1983) Fetal echocardiography. III. The diagnosis of cardiac arrhythmias using real-time-directed M-mode ultrasound. Am J Obstet Gynecol 146: 792

    Google Scholar 

  • Etches PC, Lemons J A (1979) Nonimmune hydrops fetalis: Report of 22 cases including three siblings. Pediatrics 64: 326

    PubMed  CAS  Google Scholar 

  • Fleischer AC, Killam AP, Boehm FH, Hutchison AA, Jones TB, Shaff MI, Barrett JM, Lindsey AM, James AE (1981) Hydrops fetalis: Sonographic evaluation and clinical implications. Radiology 141: 163

    Google Scholar 

  • Golbus MS (1984) The status of fetoscopy and fetal tissue sampling. Prenat Diagn 4: 79

    Article  Google Scholar 

  • Hansmann M (1981) Nachweis und AusschluB fetaler Entwicklungsstorungen mittels Ultraschallscreening und gezielter Untersuchung — ein Mehrstufenkonzept. Ultraschall 2: 206

    Article  Google Scholar 

  • Hansmann M, Redel DA (1982) Prenatal symptoms and clinical management of heart disease. In: ler symposium international d’echocardiologie foetale. Strasbourg 1982,p 137

    Google Scholar 

  • Hansmann M, Gembruch U (1984) Symptome und Behandlung moglicher fetaler Herzkrankheiten. 93. Tagung der Nordwestdeutschen Gesellschaft fur Gynakologie und Geburtshilfe. Alete Wissenschaftlicher Dienst, München, S. 56

    Google Scholar 

  • Hansmann M, Redel DA, Fodisch HJ (1982) Premature obstruction of the foramen ovale detected, treated and reconfirmed by help of ultrasound. In: Burruto F, Hansmann M, Wladimiroff JW (eds) Fetal ultrasonography: The secret prenatal life. Wiley, Chichester New York, p 151

    Google Scholar 

  • Hutchison AA, Drew JH, Yu VYH, Williams ML, Fortune DW, Beischer NA (1982) Nonimmunologic hydrops fetalis: a review of 61 cases. Obstet Gynecol 59: 347

    PubMed  CAS  Google Scholar 

  • Kleinman CS, Donnerstein RL, DeVore GR, Jaffe CC, Lynch DC, Berkowitz RL, Talner NS, Hobbins JC (1982) Fetal echocardiography for evaluation of in utero congestive heart failure. N Engl J Med 306: 568

    Article  PubMed  CAS  Google Scholar 

  • Kleinman CS, Donnerstein RL, Jaffe CC, DeVore GR, Weinstein EM, Lynch DC, Talner NS, Berkowitz RL, Hobbins JC (1983) Fetal echocardiography. A tool for evaluation of in utero cardiac arrhythmias and monitoring of in utero therapy: Analysis of 71 patients. Am J Cardiol 51: 237

    Article  PubMed  CAS  Google Scholar 

  • Macafee CAJ, Fortune DW, Beischer NA (1970) Nonimmunological hydrops fetalis. Br J Obstet Gynaecol 77: 226

    Article  CAS  Google Scholar 

  • Machin GA (1981) Differential diagnosis of hydrops fetalis. Am J Med Genet 9: 341

    Article  PubMed  CAS  Google Scholar 

  • Maidman JE, Yeager C, Anderson V, Makabali G, O’Grady P, Arce J, Tishler DM (1980) Prenatal diagnosis and management of nonimmunologic hydrops fetalis. Obstet Gynecol 56: 571

    PubMed  CAS  Google Scholar 

  • Perlin BM, Pomerance JJ, Schifrin BS (1981) Nonimmunologic hydrops fetalis. Obstet Gynecol 57: 584

    PubMed  CAS  Google Scholar 

  • Potter EL (1983) Universal edema of the fetus unassociated with erythroblastosis. Am J Obstet Gynecol 46: 130

    Google Scholar 

  • Redel DA, Hansmann M (1981) Fetal obstruction of the foramen ovale detected by two-dimensional doppler echocardiography. In: Rijsterborgh H (ed) Echocardiology. Nijhoff, The Hague Boston London, p 425

    Chapter  Google Scholar 

  • Redel DA, Hansmann M (1982) Prenatal diagnosis and treatment of heart disease. In: ler symposium international d’echocardiologie foetale. Strasbourg 1982, p 137

    Google Scholar 

  • Redel DA, Hansmann M (1984) Fetale Echokardiographie — ihre Anwendung in Diagnostik und Therapie. Gynakologe 17: 41

    PubMed  CAS  Google Scholar 

  • Rodeck CH, Nicolaides KH (1984) Die Anwendung der Fetoskopie bei fetaler Therapie. Gynakologe 17: 52

    PubMed  CAS  Google Scholar 

  • Rudolph A (1974) Congenital diseases of the heart. Year Book Medical Publishers, Chicago

    Google Scholar 

  • Schwartz SM, Viseskul C, Laxova R, McPherson EW, Gilbert EF (1981) Idiopathic hydrops fetalis. Report of 4 patients including 2 affected sibs. Am J Med Genet 8: 59

    Article  PubMed  CAS  Google Scholar 

  • Senft HH, Fodisch HJ, Hansmann M (1982) Hydrops fetalis. Fragen der pra- und postnatalen Diagnostik sowie der Pathogenese. Verh Dtsch Ges Pathol 66: 164

    PubMed  CAS  Google Scholar 

  • Staab D, Schlemminger R, Emons D, Hansmann M, Kowalewski S (1984) Darmperforation als Ursache des fetalen Aszites. INA Bd47. Kowalewski S (ed) Padiatrische Intensivmedizin VI. Thieme, Stuttgart New York, S. 86

    Google Scholar 

  • Turski DM, Shahadi N, Viseskul C, Gilbert E (1978) Non-immunologic hydrops fetalis. Am J Obstet Gynecol 131: 586

    PubMed  CAS  Google Scholar 

Download references

Authors
  1. Prof. Dr. Mandfred Hansmann
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Prof. Dr. Bernhard-Joachim Hackelöer
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Dr. med. Alfons Staudach
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Obstetrics and Gynecology, Canada

    Bernd K. Wittmann (Associate Professor, Director) (Associate Professor, Director)

  2. Department of Diagnostic Ultrasound, Grace Hospital, 4490 Oak Street, Vancouver, B.C., Canada, VGH3V5

    Bernd K. Wittmann (Associate Professor, Director) (Associate Professor, Director)

Rights and permissions

Reprints and permissions

Copyright information

© 1986 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Hansmann, M., Hackelöer, BJ., Staudach, A. (1986). Rhesus Incompatibility and Nonimmunologic Hydrops Fetalis. In: Wittmann, B.K. (eds) Ultrasound Diagnosis in Obstetrics and Gynecology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70423-9_9

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-70423-9_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-70425-3

  • Online ISBN: 978-3-642-70423-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation