Abstract
The stratum corneum serves as a barrier between viable tissue and the external environment. Its various functions include protection against toxic hazards, trauma, microbes, UV-light and thermal stimuli as well as conservation of water balance. Corneocytes are the building blocks of the stratum corneum. Their structure and biochemistry can be studied with non-invasive methods in the desquamating portion of the stratum corneum. This may help to gain some insight into the biology of the stratum corneum as a whole.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Bremner W, Scheuber E, Plewig G (1983) Effects of isotretinoin (13-cis retinoic acid, Ro 4–3780) treatment on exfoliative cytology. In: Marks R, Plewig G (eds) Stratum corneum. Springer, Berlin Heidelberg New York, pp 222–226
Delforno C, Holt PJA, Marks R (1978) Corticosteroid effect on epidermal cell size. Br J Dermatol 98: 619–623
Gahm J (1963) Durchlicht-Interferenz-Einrichtung nach Jamin-Lebedeff. Zeiss-Mitteilungen 2 /10: 389
German H, Barran W, Plewig G (1980) Morphology of corneocytes from human nail plates. J Invest Dermatol 74: 115–118
Goldschmidt H (1979) Surface area measurements of psoriatic corneocytes: Effects of intralesional steroid therapy. J Invest Dermatol 73: 558–560
Goldschmidt H, Kligman AM (1967) Exfoliative cytology of human horny layer. Arch Dermatol 96: 572–576
Grove GL, Kligman AM (1983) Corneocyte size as an indirect measure of epidermal proliferative activity. In: Marks R, Plewig G (eds) Stratum corneum. Springer, Berlin Heidelberg New York, pp 191–195
Grove GL, Lavker RM, Hölzle E, Kligman AM (1980) Use of nonintrusive tests to monitor age-associated changes in human skin. J Soc Cosm Chem 32: 15–26
Heilmann BB, Ryckmanns F, Plewig G (1983) Scanning electron microscopy of human corneocytes. In: Marks R, Plewig G (eds) Stratum corneum. Springer, Heidelberg New York, pp 186–190
Herrmann S, Scheuber E, Plewig G (1983) Exfoliative cytology: Effects of the seasons. In: Marks R, Plewig G (eds) Stratum corneum. Springer, Berlin Heidelberg New York, pp 181–185
Hölzle E, Park J, Plewig G (1980) Einfluß verschiedener Glukokortikoide und ihrer Grundlagen auf die Korneozyten der normalen Epidermis. Aktuel Dermatol 6: 75–81
Hölzle E, Plewig G (1977) Effects of dermatitis, stripping and steroids on the morphology of corneocytes: A new bioassay. J Invest Dermatol 68: 350–356
King CS, Dykes PJ, Marks R (1983) Preparation and immunochemical analysis of non-ionic detergent-soluble protein from human stratum corneum. In: Marks R, Plewig G (eds) Stratum corneum. Springer, Berlin Heidelberg New York, pp 68–72
Marks R. Dawber RPR (1971) Skin surface biopsy: An improved technique for the examination of the horny layer. Br J Dermatol 84: 117–123
Marks R, Nicholls S, King CS (1981) Studies on isolated corneocytes. Internat J Cosmet Science 3: 251–258
McGinley KJ, Marples RR, Plewig G (1969) A method for visualizing and quantitating the desquamating portion of the human stratum corneum. J Invest Dermatol 53: 107–111
Plewig G, Marples RR (1970) Regional differences of cell sizes in the human stratum corne-um, part I. J Invest Dermatol 54: 13–18
Plewig G, Scheuber E, Reuter B, Waidelich W (1983) Thickness of corneocytes. In: Marks R, Plewig G (eds) Stratum corneum. Springer, Berlin Heidelberg New York, pp 171–174
Rogall P (1976) GröAe von Hornzellen und Schleimhautzellen in Abhängigkeit vom Alter. Dissertation, Dept Dermatol, University of Munich, FRG
Stein W (1978) Hornzellmorphologie exsikkierter Altershaut. Verlaufsmessungen. Dissertation, Dept Dermatol, University of Munich, Munich, FRG
Wolf J (1939) Die innere Struktur der Zellen des Stratum desquamans der menschlichen Epidermis. Zeitschr Mikroskop-Anatom Forschung 46: 170–202
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1986 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Hölzle, E., Plewig, G., Ledolter, A. (1986). Corneocyte Exfoliative Cytology: A Model to Study Normal and Diseased Stratum Corneum. In: Marks, R., Plewig, G. (eds) Skin Models. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70387-4_22
Download citation
DOI: https://doi.org/10.1007/978-3-642-70387-4_22
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-70389-8
Online ISBN: 978-3-642-70387-4
eBook Packages: Springer Book Archive