Ultrafiltration During Cardiopulmonary Bypass

  • D. J. Magilligan


Crystalloid prime with hemodilution has been a great advantage to cardiac surgeons, for in addition to decreasing blood requirements it has also resulted in improved pulmonary and renal function [1]. Postoperative weight gain and an increase of up to 33% in the measured extracellular fluid space [2] are the disadvantages of dilution perfusion. In most patients this excess water is well tolerated and rapidly excreted. Certainly in renal failure patients, this excess fluid load may be detrimental. However, we are also interested in patients with severe preoperative fluid overload, in whom, even with adequate renal function, the additional water volume particularly in the lungs, may lead to organ dysfunction. We first set out to evaluate the use of ultrafiltration during cardiopulmonary bypass in a laboratory setting and have now instituted its use in a clinical setting. The following is a report of that experience.


Cardiopulmonary Bypass Bypass Flow Extravascular Lung Water Hydrostatic Pressure Gradient Recirculation Line 
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© Springer-Verlag Berlin Heidelberg 1985

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  • D. J. Magilligan

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