Bacterial Growth on Biomaterials
A device was developed to replace the test tube in determining the adherence, growth, and inhibition of growth of bacteria on biomaterials (Fig. 1). The fluids of interest include serum, synovial fluid, urine, or another body fluid or secretion. The test sample with bacteria is allowed to flow through the device The build up of the mass of organisms on the surface occurs in a short period of time (Fig. 2). The discs can then be removed and put into a system to test for phagocytosis of the attached organisms, for serum killing, for specific antibody effects, or for the determination of the efficacy of antibacterials against bacteria that are adherent to a surface.