Hematological and Oncological Indications for Splenectomy in Children

  • C. Urban
  • M. Höllwarth
  • W. Kaulfersch
  • I. Slavc
Conference paper
Part of the Progress in Pediatric Surgery book series (PEDIATRIC, volume 18)

Abstract

The importance of the spleen as an organ of resistance has been shown, and it has been emphasized that the spleen should be preserved whenever possible. Nevertheless, there are indications that in hematologic diseases, the spleen, just because of its increased phagocytic activity, must be removed (Gill 1980; Philippart and Hight 1980).

Keywords

Lymphoma Leukemia Anemia Penicillin Oncol 

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References

  1. Ahn YS, Harrington WJ (1977) Treatment of idiopathic thrombocytopenic purpura (ITP). Ann Rev Med 28:299–309PubMedCrossRefGoogle Scholar
  2. Boles ET Jr, Haase GM, Hamoudi AB (1979) Partial splenectomy in staging laparotomy for Hodgkin’s disease: an alternative approach. J Pediatr Surg 13:581–586CrossRefGoogle Scholar
  3. Chilcote RR, Baehner RL, Hammond D (1976) Septicemia and meningitis in children splenectomized for Hodgkin’s disease. N Engl J Med 295:798PubMedCrossRefGoogle Scholar
  4. Dickerman JD (1979) Splenectomy and sepsis: a warning. Pediatrics 63:938–939PubMedGoogle Scholar
  5. Donaldson SS, Glatstein E, Vosti K (1978) Bacterial infections in pediatric Hodgkin’s disease: relationship to radiotherapy, chemotherapy and splenectomy. Cancer 41:1949–1958PubMedCrossRefGoogle Scholar
  6. Anonymous (1976) Infective hazards of splenectomy. Editorial. Lancet 1:167–168Google Scholar
  7. Ell C, Reim E (1982) Hochdosierte Immunglobulin-Therapie bei chronischer idiopathischer thrombozytopenischer Purpura. Dtsch Med Wochenschr 107:1211–1212Google Scholar
  8. Gahr M (1981) Erythrozytenenzymdefekte — Klinik und Pathophysiologic. Monatsschr Kinderheilkd 129:444–453PubMedGoogle Scholar
  9. Gill FM (1980) Hematologic indications for splenectomy in pediatrics. Am J Pediatr Hematol Oncol 2:41–52Google Scholar
  10. Gill PG, Souter RG, Morris PJ (1981) Splenectomy for hypersplenism in malignant lymphomas. Br J Surg 68:29–33PubMedCrossRefGoogle Scholar
  11. Gomez GA, Sokal JE, Mittelman A, August CW (1976) Splenectomy for palliation of chronic myelocytic leukemia. Am J Med 61:14–22PubMedCrossRefGoogle Scholar
  12. Harouchi A, Benchemsi N, Benouhoud M (1982) La ligature de l’artere splenique d’indication hematologique chez l’enfant. Chir Pediatr 23:109–113PubMedGoogle Scholar
  13. Imbach P, D’Apuzzo V, Hirt A, Rossi E, Vest M, Barandun S, Baumgartner C, Morell A, Schöni M, Wagner HP (1981) High dose intravenous gammaglobulin for idiopathic thrombocytopenic purpura in childhood. Lancet 1:1228–1231PubMedCrossRefGoogle Scholar
  14. Isa SS, Mirkij NJ, Firzli SS, Slim MS (1974) Post-splenectomy infections in childhood. Z Kinderchir 14:245–251Google Scholar
  15. Kellerer K, Mutz I (1976) Chronische pseudomaligne Immunproliferation (Canale-Smith-Syndrom). Eur J Pediatr 121:203–213PubMedCrossRefGoogle Scholar
  16. Mutz I, Muntean W (1976) Intrakranielle Blutung bei idiopathischer thrombozytopenischer Purpura (ITP). Klin Pediatr 188:548–551Google Scholar
  17. Philippart AI, Hight DW (1980) Splenectomy in childhood. Altered concepts of management. Am J Pediatr Hematol Oncol 2:61–68Google Scholar
  18. Rutkow IM (1981) Twenty years of splenectomy for hereditary spherocytosis. Arch Surg 116: 306–308PubMedGoogle Scholar
  19. Schellong G, Waubke AK, Langermann HJ, Breu H, Kühne B, Riehm H, Ritter J (1982) Bedeutung klinischer und intraoperativer Befunde für die Voraussage eines Milzbefalls beim Morbus Hodgkin im Kindesalter: Eine retrospektive statistische Analyse bei 154 Patienten der Therapiestudie HD 78. Klin Pädiatr 194:242–250PubMedCrossRefGoogle Scholar
  20. Schröter W, Wonneberger B (1976) Klinik und Biochemie des Pyruvatkinasemangels. I. Klinische und hämatologische Untersuchungen. Monatsschr Kinderheilkd 124:1–8PubMedGoogle Scholar
  21. Stögmann W, Paky F (1980) Postsplenektomiesepsis. Pädiatr Praxis 23:429–433Google Scholar
  22. Thanopoulos BD, Frimas CA (1982) Partial splenic embolization in the management of hyper-splenism secondary to Gaucher disease. J Pediatr 101:740–743PubMedCrossRefGoogle Scholar
  23. Tillmann W, Schröter W (1982) Erythrozytenrheologie und Indikation zur Splenektomie bei kongenitalen hämolytischen Anämien. Monatsschr Kinderheilkd 130:254–266PubMedGoogle Scholar
  24. Urban C, Hackl A, Kurz R, Becker H, Mutz I (1981) Probleme des Morbus Hodgkin im Kindesalter. Onkologie 4:331–341PubMedCrossRefGoogle Scholar
  25. Wündisch GF (1980) Antibiotische Prophylaxe nach Milzexstirpation. Pädiatr Praxis 23:433–434Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • C. Urban
    • 1
  • M. Höllwarth
    • 2
  • W. Kaulfersch
    • 1
  • I. Slavc
    • 1
  1. 1.Universitäts-KinderklinikGrazAustria
  2. 2.Universitätsklinik für KinderchirurgieGrazAustria

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