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Thyroid Function in Children on CAPD

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CAPD in Children

Abstract

Thyroid function in uremia has not been studied as extensively in children as it has been in adults. The data available point to a low T3 and T4 syndrome, but it is not clear whether these patients are hypothyroid or not [1–5]. In addition, little is known about free hormone concentration with respect to the various dialytic modalities for this age group of patients. This work was designed to study thyroid function in children undergoing CAPD. The data presented indicate that CAPD does not correct the low T3 and T4 syndrome. In addition, stunted TSH response to TRH is present.

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References

  1. Czernichow P, Dauzet MC, Broyer M, Rappaport R (1976) Abnormal TSH, PRL and GH response to TSH releasing factor in chronic uremia. J Clin Endocrinol Metab 43:630

    Article  PubMed  CAS  Google Scholar 

  2. Wassner JJ, Buckingham BA, Kershar AJ, Malekzadeh MH, Pennisi AJ, Fine RN (1977) Thyroid function in children with chronic renal failure. Nephron 19:236

    Article  PubMed  CAS  Google Scholar 

  3. Chan JCM, Hung W (1978) Hemodialysis and thyroid function in children. J Dial Transplant 2:387

    CAS  Google Scholar 

  4. Waters W, Bulla M, Tekook A (1982) Thyroid function in children on regular hemodialysis. In: Bulla M (ed) Renal insufficiency in children. Springer, Berlin Heidelberg New York, p 129

    Chapter  Google Scholar 

  5. De Santo NG, Fine RN, Carella C, Leumann E, Amato G, Fine S, Nuzzi F, Capasso G, Capodicasa G, Lama G, Scoppa F, and Giordano C. Thyroidal status in uremic children. Kidney Int (in press)

    Google Scholar 

  6. Giordano C, Carella C, De Santo NG, Mioli V, Bazzato G, Amato G, Tarchini A, Coli U, Landini S (1982) Hormonal status of patients on CAPD and HD. In: La Greca G (ed) Proceedings 1st international course on peritoneal dialysis. Wichtig, Milan, p 330

    Google Scholar 

  7. Giordano C, De Santo NG, Carella C, Mioli V, Bazzato G, Di Leo Va, Amato G, Tarchini A, Coli V, Landini S (1982) Thyroid status in uremia, effects of hemodialysis and CAPD. Int JArtif Organs 5:394

    Google Scholar 

  8. Giordano C, De Santo NG, Carella C, Mioli V, Bazzato G, Amato G, Tarchini A, Coli V, Capasso G, Landini V, Capodicasa G, Nuzzi F, Esposito A. Thyroidal function during hemodialysis and CAPD. Proceedings 4th ISAO Conference. Artif Organs (in press)

    Google Scholar 

  9. Giordano C, De Santo NG, Carella C, Mioli V, Bazzato G, Amato G, Di Leo VA, Tarchini G, Coli U, Capodicasa G, Landini G, Nuzzi F, De Simon V, Esposito A (1984) TSH response to TRH in hemodialysis and CAPD patients. Int J Artif Organs 7:7

    PubMed  CAS  Google Scholar 

  10. Giordano C, De Santo NG, Carella C, Capodicasa G, Amato G, Nuzzi F, Mioli V, Bazzato G, De Simone V, Tarchini A, Landini A, Coli U, Bordoni V, Mottola G, Capuano F (1984) Thyroid status and nephron loss. A study in patients with chronic renal failure, end stage renal disease and/or on hemodialysis. Int J Artif Organs 7:119

    PubMed  CAS  Google Scholar 

  11. Ramirez G, Jubitz W, Gutch CF, Bloomer HA, Siegler R, Kolff WJ (1973) Thyroid abnormalities in renal failure. A study on 53 patients on chronic hemodialysis. Ann Intern Med 79:504

    Google Scholar 

  12. Carter JN, Eastman CJ, Corcoran P, Lazarus L (1974) Effects of severe illness on thyroid function. Lancet 2:971

    Article  PubMed  CAS  Google Scholar 

  13. Spector DA, Davis JP, Helderman JH, Bell B, Utiger RD (1976) Thyroid function and metabolic state in chronic renal failure. Ann Intern Med 85:274

    Google Scholar 

  14. Savdie E, Stewart JH, Mahony JF, Hayer JM, Lazarus L, Simons LA (1978) Circulating thyroid hormone levels and adequacy of dialysis. Clin Nephrol 9:68

    PubMed  CAS  Google Scholar 

  15. Weissel M, Stummval HK, Wolf A, Fritsche H (1977) Thyroid hormone in chronic renal failure. Ann Intern Med 86:644

    Google Scholar 

  16. Kalk WJ, Morley JE, Gold GH, Meyers A (1980) Thyroid function tests in patients on regular hemodialysis. Nephron 25:173

    Article  PubMed  CAS  Google Scholar 

  17. Farrington K, Boss AMB, Varghese Z, Kingstone D, Baillod RA, Moorhead JF (1980) Thyroid function tests in dialyzed patients. Dial Transplant 9:846

    Google Scholar 

  18. Czekalski S, Malczeva B, Sobieszczyk S, Kozak W, Eder M, Grycynska M, Backzyk K, Kosowicz J (1981) Comparison of some circulating pituitary thyroid and gonadal hormone levels in non dialyzed and dialyzed males with chronic renal failure. Dial Transplant 10:438

    Google Scholar 

  19. Nogimori T (1981) A Clinical study on thyroid hormone secretion and metabolism in patients with chronic renal failure on hemodialysis. Folia Endocrinol (Jpn) 57:903

    CAS  Google Scholar 

  20. Gavin LA, McMahon FA, Castle JN, Cavalier RC (1970) Alternions in serum thyroid hormones and thyroxin binding globulin in patients with nephrosis. J Clin Endocrinol Metab 49:63

    Google Scholar 

  21. Kaptein EM, MacIntyre SS, Weiner SM, Spencer CA, Nicoloff JT (1981) Free thyroxine estimates in non thyroidal illness. Comparison of eight methods. J Clin Endocrinol Metab 52:1073

    Article  PubMed  CAS  Google Scholar 

  22. Penny R, Spencer CA, Frasier DS, Nicoloff JT (1983) Thyroid stimulating hormone and thyroglobulin levels decrease with chronological age in children and adolescents. J Clin Endocrinol Metab 56:177

    Article  PubMed  CAS  Google Scholar 

  23. De Santo NG, Carella C, Fine RN, Leumann E, Fine S, Amato G, Capodicasa G, Nuzzi F, Capasso G, Lama G, Scoppa F, De Simone V, Giordano C (1984) Data presented at Bari Seminars in nephrology 29–31 March

    Google Scholar 

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© 1985 Springer-Verlag Berlin Heidelberg

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De Santo, N.G. et al. (1985). Thyroid Function in Children on CAPD. In: Fine, R.N., Schärer, K., Mehls, O. (eds) CAPD in Children. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70213-6_16

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  • DOI: https://doi.org/10.1007/978-3-642-70213-6_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-70215-0

  • Online ISBN: 978-3-642-70213-6

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