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The Role of Specific Antibodies in Different Immunoglobulin Classes in the Rapid Diagnosis of Diseases Caused by Treponemes

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Rapid Methods and Automation in Microbiology and Immunology

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Abstract

Treponemal infections like sexually transmitted syphilis, endemic syphilis, yaws, or pinta can be cured in all stages by specific treatment. However, these infections can also cure without any therapy, i.e., spontaneously. In the early stages of treponematoses, particularly in sexually transmitted syphilis, the demonstration of the causative agent in lesions is the diagnostic method of choice. But identification of T. pallidum is often unsuccessful because of several eventualities. In many individuals where there are clinical or epidemiological grounds for suspecting a treponemal infection, it is therefore necessary to provide the diagnosis from the humoral immune response of the infected organism.

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Author information

Authors and Affiliations

  1. Abteilung für Infektionsimmunologie, Hygienischen Institut der Freien Hansestadt Hamburg, Gorch-Fock-Wall 15/17, D-2000, Hamburg 36, Germany

    F. Müller

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  1. F. Müller
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Editors and Affiliations

  1. Institut für Klinische und Experimentelle Virologie, Freie Universität Berlin, Hindenburgdamm 27, D-1000, Berlin 45, Germany

    K.-O. Habermehl

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© 1985 Springer-Verlag Berlin Heidelberg

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Müller, F. (1985). The Role of Specific Antibodies in Different Immunoglobulin Classes in the Rapid Diagnosis of Diseases Caused by Treponemes. In: Habermehl, KO. (eds) Rapid Methods and Automation in Microbiology and Immunology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69943-6_22

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  • DOI: https://doi.org/10.1007/978-3-642-69943-6_22

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-69945-0

  • Online ISBN: 978-3-642-69943-6

  • eBook Packages: Springer Book Archive

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