Part of the Archives of Toxicology book series (TOXICOLOGY, volume 8)
Pharmokinetics of Metoprolol in Relation to Polymorphic Sparteine Oxidation
A close correlation between the polymorphic 4-hydroxylation of debrisoquine and the pharmacokinetics of the beta-adrenoceptor antagonist metoprolol has been reported recently (Lennard et al., 1982).
Key wordsGenetic Polymorphism Sparteine Metoprolol
© Springer-Verlag 1985