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Changes of Haemostaseological Variables in Carbon Tetrachloride Poisoning in Rats

  • Conference paper
Receptors and Other Targets for Toxic Substances

Part of the book series: Archives of Toxicology ((TOXICOLOGY,volume 8))

  • 194 Accesses

Abstract

On application of carbon tetrachloride to rats disturbances of haemostasis were observed. Antithrombin III and 4-amidinophenylpyruvic acid were found to exert a beneficial action on these disturbances. However, the thrombin inhibitors had no influence on hepatotoxicity and lethality.

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References

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Author information

Authors and Affiliations

  1. Institute of Pharmacology and Toxicology, Medical Academy Erfurt, Nordhäuser Str. 74, DDR-5010, Erfurt, GDR

    H.-P. Klöcking, H. Müller & F. Markwardt

Authors
  1. H.-P. Klöcking
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  2. H. Müller
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  3. F. Markwardt
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Editor information

Editors and Affiliations

  1. Department of Pharmacology and Therapeutics, Trinity College, University of Dublin, Dublin 2, Ireland

    Philip L. Chambers  & Claire M. Chambers  & 

  2. Pharmacological Research Centre, Toxicological Service, Chemical Works of Gedeon Richter Ltd., P.O. Box 27, 1475, Budapest, Hungary

    Eszter Cholnoky

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© 1985 Springer-Verlag

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Klöcking, HP., Müller, H., Markwardt, F. (1985). Changes of Haemostaseological Variables in Carbon Tetrachloride Poisoning in Rats. In: Chambers, P.L., Cholnoky, E., Chambers, C.M. (eds) Receptors and Other Targets for Toxic Substances. Archives of Toxicology, vol 8. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69928-3_22

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  • DOI: https://doi.org/10.1007/978-3-642-69928-3_22

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-13670-5

  • Online ISBN: 978-3-642-69928-3

  • eBook Packages: Springer Book Archive

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