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Prostaglandins and Inhibitors

  • O. Oetliker
  • E. Sulyok
  • H. W. Seyberth
  • L. Wille
  • H. E. Ulmer
  • W. Rascher
Conference paper

Abstract

As an introduction to this section on prostaglandins I would like to present a number of reasons why prostaglandins are of interest to nephrologists.

Keywords

Patent Ductus Arteriosus Plasma Renin Activity Renin Angiotensin Aldosterone System Indomethacin Therapy Vasodilatory Prostaglandin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Arisz L, Donker AJM, Brentjens JRH, van der Hem GK (1976) The effect of indomethacin on proteinuria and kidney function in the nephrotic syndrome. Acta Med Scand 199: 121–125PubMedCrossRefGoogle Scholar
  2. Beitz J, Förster W (1981) Differential influence of lipoproteins isolated from women and men on the activity of the PGI2 synthetase activity. Prostaglandins Med 6: 515–518PubMedCrossRefGoogle Scholar
  3. Berl T (1981) Cellular calcium uptake in the action of prostaglandins on renal water excre-tion. Kidney Int 19: 15–23PubMedCrossRefGoogle Scholar
  4. Dunn MJ, Liard JF, Dray F (1978) Basal and stimulated rates of renal secretion and excretion of prostaglandins E2, Fa and 13, 14-dihydro-15-keto Fa in the dog. Kidney Int 13: 136–143Google Scholar
  5. Dunn MJ, Zambraski EJ (1980) Renal effects of drugs that inhibit prostaglandin synthesis. Kidney Int 18: 609–622PubMedCrossRefGoogle Scholar
  6. Fine LG, Kirschenbaum MA (1981) Absence of direct effects of prostaglandins on sodium chloride transport in the mammalian nephron. Kidney Int 19; 797–801PubMedCrossRefGoogle Scholar
  7. Gerber JG, Olson RD, Nies AS (1981) Interrelationship between prostaglandins and renin release. Kidney Int 19: 816–821PubMedCrossRefGoogle Scholar
  8. Granström E, Kindahl H (1978) Radioimmuno-assay of prostaglandins and thromboxanes. In: Frölich (ed) Advances in prostaglandin and thromboxane research, vol 5. Raven NY, pp 119–210Google Scholar
  9. Janggen H, Janggen FM, Lüthy CH, Siegrist M, Oetliker O (1984) Interrelation of lipoproteins and prostaglandin metabolism of cultured human skin fibroblast. (Manuscript in preparation )Google Scholar
  10. Kirschenbaum MA, Serros ER (1980) Are prostaglandins natriuretic? Mineral Electrolyte Metab 3: 112–121Google Scholar
  11. Kokko JP (1981) Effect of prostaglandins on renal epithelial electrolyte transport. Kidney Int 19: 791–796PubMedCrossRefGoogle Scholar
  12. Lerman RI, Pitcook JA, Stephenson P, Muirhead EE (1972) Renomedullary interstitial cell tumor (formerly fibroma of renal medulla). Human Pathol 3: 559–568CrossRefGoogle Scholar
  13. Lüthy CH, Multhaupt M, Oetliker O, Perisic M (1983) Differential effect of acetylsalycilic acid and dipyrone on prostaglandin production in human fibroblast cultures. Br J Pharmacol 79: 849–854PubMedGoogle Scholar
  14. Matson JR, Stokes JB, Robillard JE (1981) Effects of inhibition of prostaglandin synthesis on fetal renal function. Kidney Int 20: 621–627PubMedCrossRefGoogle Scholar
  15. Moncada S, Gryglewski RJ, Bunting S, Vane JR (1976) An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation. Nature (London) 263: 663–665CrossRefGoogle Scholar
  16. Moncada S, Vane RJ (1981) Prostacyclin: Homeostatic regulator or biological curiosity? Clin Sci 61: 369–372PubMedGoogle Scholar
  17. Muirhead EE, Germain G, Leach BE, Pitcock JA, Stephenson P, Brooks B, Brosins WL, Daniels EG, Kinman JW (1972) Production of renomedullary prostaglandins by renomedullary interstitial cells grown in tissue culture. Circ Res 30–31 [Suppl 2]: 161–172Google Scholar
  18. Milliner G, Gähwiler T, Lüthy C, Oetliker O, Dillon J, Rosa F (1983) Comparison of prostaglandin production of skin fibroblasts grown from patients with Bartters’s syndrome and from age and sex matched controls. Prostaglandins Med 11: 83–93CrossRefGoogle Scholar
  19. Nasjletti A, Malik KU (1981) Interrelationship between prostaglandins and renin release. Kidney Int 19: 860–868PubMedCrossRefGoogle Scholar
  20. Szczeklik A, Gryglewski RI, Nizankowski R, Musial J, Pieton R, Mruk J (1978) Circulatory and anti-platelet effects of intravenous prostacyclin in healthy men. Pharmacol Res Commun 10: 545–556PubMedCrossRefGoogle Scholar
  21. Vane JR (1983) Prostaglandins and the cardiovascular system. Br Heart J 49: 405–409PubMedCrossRefGoogle Scholar
  22. Zimmermann A, Luscieti P, Flury B, Hess M, Cottier H (1981) Amyloid-containing renal in-terstitial cell nodules associated with chronic arterial hypertension in older age groups. Am J Pathol 105: 288–294PubMedGoogle Scholar
  23. Ertl T, Sulyok E, Németh M, Tényi I, Csaba IF, Varga F (1982) The effect of sodium chloride supplementation on the postnatal development of plasma prostaglandin E and F2 α, values in premature infants. J Pediatr 101: 761PubMedCrossRefGoogle Scholar
  24. Grantham J, Orloff J (1968) Effect of prostaglandin E1 on the permeability response of the isolated collecting tubule to vasopressin, adenosin 3’,5’-monophosphate and theophylline. J Clin Invest 47: 1154PubMedCrossRefGoogle Scholar
  25. Joppich R, Häuser I (1982) Urinary prostaglandin and thromboxane A2 metabolites in pre-term and full-term infants in relation to plasma renin activity and blood pressure. Biol Neonate 42: 179PubMedCrossRefGoogle Scholar
  26. Joppich R, Scherer B, Weber PC (1979) Renal prostaglandins: Relationship to the development of blood pressure and concentrating capacity in preterm and fullterm healthy infants. Eur J Pediatr 132: 253PubMedCrossRefGoogle Scholar
  27. Joppich R, Haberle DA, Weber PC (1981) Studies on the immaturity of the ADH-dependent cAMP system in conscious newborn piglets — possible impairing effects of renal prostaglandins. Pediatr Res 15: 278PubMedCrossRefGoogle Scholar
  28. Matson JR, Stokes JB, Robillard JE (1981) The effect of inhibition of prostaglandin synthesis on the fetal renal function. Kidney Int 20: 621PubMedCrossRefGoogle Scholar
  29. McGiff JC (1981) Prostaglandins, prostacyclin and thromboxanes. Ann Rev Pharmacol Toxicol 21: 479CrossRefGoogle Scholar
  30. Robillard JE, Gomez RA, VanOrden D, Smith FG (1982a) Comparison of the adrenal and renal responses to angiotensin II in fetal lambs and adult sheep. Circ Res 50: 140Google Scholar
  31. Robillard JE, Lawton WJ, Weismann DN, Sessions C (1982b) Developmental aspects of the renal kallikrein-like activity in fetal and newborn lambs. Kidney Int 22: 594CrossRefGoogle Scholar
  32. Stokes JB (1981a) Prostaglandins and the regulation of NaCl transport across renal epithelia. Miner Electr Metab 6: 35Google Scholar
  33. Stokes JB (1981b) Integrated actions of renal medullary prostaglandins in the control of water excretion. Am J Physiol 240: F471Google Scholar
  34. Sulyok E, Ertl T, Csaba IF, Varga F (1980) Postnatal changes in urinary PGE excretion in premature infants. Biol Neonate 37: 192PubMedCrossRefGoogle Scholar
  35. Terragno NA, McGiff JC, Smigel M, Terragno DA (1978) Patterns of prostaglandin production in the bovin fetal and maternal vasculate. Prostaglandins 16: 847CrossRefGoogle Scholar
  36. Tsuruta K, Iihoshi M, Soejima H, Ikegami K (1979) Intrarenal prostaglandins: effect of sodium and indomethacin on PGE2 and PGF2o, in rabbits. Nephron 24: 283PubMedCrossRefGoogle Scholar
  37. Yabek SM, Avner BP (1979) Effects of prostaglandin E1 and indomethacin on fetal and neonatal lamb mesenteric artery responses to norepinephrine. Prostaglandins 17: 227PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin, Heidelberg 1984

Authors and Affiliations

  • O. Oetliker
  • E. Sulyok
  • H. W. Seyberth
  • L. Wille
  • H. E. Ulmer
  • W. Rascher

There are no affiliations available

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