Abstract
During the Seventh Workshop, WIA4x7 was described with a set of sera containing activity for both DR4 and DR7. During the Eighth Workshop, new facts were observed:
-
1.
The specificity IA4x7 was defined by duo- or trispeciflc antisera [1]
-
2.
The Japanese specificity 7J was considered to be equivalent to IA4x7 [2–4]
-
3.
Whether IA4x7 belonged to the DR locus [5, 6] or not [7, 8] was controversial.
-
4.
The WHO Nomenclature Committee designated a part of IA4x7 as DRw9 [9]
-
5.
The determinant MT3 (DRw53) includes DR4, DR7, DRw9 and DRw10 [10]
-
6.
Finally, the binding data show that “the DR4x7 determinant, previously described as being associated with all DR4-positive and most DR7-positive individuals tested so far is represented on a molecular subset differing from both the DR4 and DR7 molecular subset, and it is probably equivalent to the DRw53 specificity detected by cytotoxicity assay.” [11].
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Colombe B, Payne R (1980) Evidence from family data for two specificities in 8W12. In: Terasaki PI (ed) Histocompatibility testing 1980. UCLA Tissue Typing Laboratory, Los Angeles, p 831
Maeda H, Juji T (1980) A new DR antigen crossreactive with DRw4 and DRw7. In: Terasaki PI (ed) Histocompatibility testing 1980. UCLA Tissue Typing Laboratory, Los Angeles, p 837
Sekiguchi S, Kobayashi K, Konoeda Y, Takata H (1980) Two components of the Ia4x7B lymphocyte antigen found in Japanese. In: Terasaki PI (ed) Histocompatibility testing 1980. UCLA Tissue Typing Laboratory, Los Angeles, p 836
Aizawa M, Wakisaka A, Morinchi J, Nakai Y, Kano T, Itakura K (1980) A new B cell allo-antigen characteristic for Orientals? In: Terasaki PI (ed) Histocompatibility testing 1980. UCLA Tissue Typing Laboratory, Los Angeles, p 826
Lung P, Hidalggo R, Giugal DP (1980) Ia4x7 B lymphocyte antigen in Caucasians. In: Terasaki PI (ed) Histocompatibility testing 1980. UCLA Tissue Typing Laboratory, Los Angeles, p 834
Kato M, Matsui C, Taniai S, Watanabe K, Kashiwagi N (1980) 7J specificity in HLA-DR antigens. In: Terasaki PI (ed) Histocompatibility testing 1980. UCLA Tissue Typing Laboratory, Los Angeles, p 839
Payne R, Colombe B (1980) On the trail of the 4x7 B lymphocyte antigen. In: Terasaki PI (ed) Histocompatibility testing 1980. UCLA Tissue Typing Laboratory, Los Angeles, p 829
Dewar PJ, Lawler SD (1980) Still on the trail of the Ia4x7 antigens. In: Terasaki PI (ed) Histocompatibility testing 1980. UCLA Tissue Typing Laboratory, Los Angeles, p 838
Colombe B, Payne R (1980) 8W12 (DRw9 + 10). In: Terasaki PI (ed) Histocompatibility testing 1980. UCLA Tissue Typing Laboratory, Los Angeles, 543
Nakata S, Park MS, Omori K (1980) MT3. Joint Report. In: Terasaki PI (ed) Histocompatibility testing 1980. UCLA Tissue Typing Laboratory, Los Angeles, p 569
Tosi R (1980) MT3. Joint Report. In: Terasaki PI (ed) Histocompatibility testing 1980. UCLA Tissue Typing Laboratory, Los Angeles, p 568
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1984 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Lepage, V., Grumet, F.C., Busson, M., Colombani, J., Ness, D., Degos, L. (1984). Antigen Report: HLA-DRw53. In: Albert, E.D., et al. Histocompatibility Testing 1984. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69770-8_86
Download citation
DOI: https://doi.org/10.1007/978-3-642-69770-8_86
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-69772-2
Online ISBN: 978-3-642-69770-8
eBook Packages: Springer Book Archive