Mouse L Cells Expressing Human HLA-DR Antigens After Transfection with Class II Genes Do Not Stimulate Human T Lymphocytes

  • T. Moen
  • C. de Préval
  • C. Rabourdin-Combe
  • B. Mach
  • G. Gaudernack
  • E. Bondevik
  • E. Thorsby
Conference paper

Abstract

The HLA class II determinants are involved in activation of T4 lymphocytes. These dimeric cell membrane molecules are glycoproteins comprised of one α and one β chain subunit and are expressed mainly on B cells and accessory lymphoid cells [7]. Recent data has revealed that the class II region most probably encompasses a complexity of loci: DR coding for three β and one α chain, DQ and DP each coding for two β and α two a chains [2, 11].

Keywords

Penicillin Glutamine Thymidine Mitomycin Tomycin 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1984

Authors and Affiliations

  • T. Moen
    • 1
  • C. de Préval
    • 2
  • C. Rabourdin-Combe
    • 2
  • B. Mach
    • 2
  • G. Gaudernack
    • 1
  • E. Bondevik
    • 1
  • E. Thorsby
    • 1
  1. 1.Institute of Transplantation ImmunologyThe National HospitalOslo 1Norway
  2. 2.Department of MicrobiologyUniversity of Geneva Medical SchoolGenevaSwitzerland

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