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Mouse L Cells Expressing Human HLA-DR Antigens After Transfection with Class II Genes Do Not Stimulate Human T Lymphocytes

  • T. Moen
  • C. de Préval
  • C. Rabourdin-Combe
  • B. Mach
  • G. Gaudernack
  • E. Bondevik
  • E. Thorsby
Conference paper

Abstract

The HLA class II determinants are involved in activation of T4 lymphocytes. These dimeric cell membrane molecules are glycoproteins comprised of one α and one β chain subunit and are expressed mainly on B cells and accessory lymphoid cells [7]. Recent data has revealed that the class II region most probably encompasses a complexity of loci: DR coding for three β and one α chain, DQ and DP each coding for two β and α two a chains [2, 11].

Keywords

Lymphoid Cell Line Murine Major Histocompatibility Complex London Hospital Medical College Homozygous Typing Cell Geneva Medical School 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1984

Authors and Affiliations

  • T. Moen
    • 1
  • C. de Préval
    • 2
  • C. Rabourdin-Combe
    • 2
  • B. Mach
    • 2
  • G. Gaudernack
    • 1
  • E. Bondevik
    • 1
  • E. Thorsby
    • 1
  1. 1.Institute of Transplantation ImmunologyThe National HospitalOslo 1Norway
  2. 2.Department of MicrobiologyUniversity of Geneva Medical SchoolGenevaSwitzerland

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