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Serological and Structural Heterogeneity of HLA-DR4 Alloantigens

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Histocompatibility Testing 1984

Abstract

Testing of a large panel of anti-class II monoclonal antibodies (MoAb) with the lymphoid cell lines FS, L-KT9, L-KT13, THO, and WALK carrying serologically indistinguishable DR4 allospecificities but different cellularly defined HLA-D allospecificities showed that the anti-HLA-DR MoAb Q2/80 displayed differential reactivity with the cell lines (Table 1).

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References

  1. Groner JP, Watson AJ, Bach FH (1983) Dw/LD-related molecular polymorphism of DR4 β-chains. J Exp Med 157: 1687–1691

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  2. Nepom BS, Nepom GT, Mickelson E, Antonelli P, Hansen JA (1983) Electrophoretic analysis of human HLA- DR antigens from HLA-DR4 homozygous cell lines: Correlation between β-chain diversity and HLA-D. Proc Natl Acad Sci USA 80: 6962–6966

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© 1984 Springer-Verlag Berlin Heidelberg

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Igarashi, M., Yoshii, M., Kashiwagi, N., Crepaldi, T., Ferrone, S. (1984). Serological and Structural Heterogeneity of HLA-DR4 Alloantigens. In: Albert, E.D., et al. Histocompatibility Testing 1984. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69770-8_182

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  • DOI: https://doi.org/10.1007/978-3-642-69770-8_182

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-69772-2

  • Online ISBN: 978-3-642-69770-8

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