Abstract
Recent structural studies have suggested that DQ molecules are more polymorphic than presently defined by conventional serology [1–3]. We have analyzed 9W reagents for the presence of sera that might detect new polymorphisms on DQ molecules. To do this, we have utilized the following criteria: (1) expression on B cells but not on most monocytes; (2) specific inhibition of cytotoxicity by monoclonal anti-DQ but not by anti-DR antibodies; (3) panel distribution distinct from the known DQwl, 2, and 3 specificities.
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© 1984 Springer-Verlag Berlin Heidelberg
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Nunez, G., Latimer, M.J., Ball, E.J., Myers, L.K., Stastny, P. (1984). Serologic Detection of New Polymorphisms on DQ Molecules Distinct from the DQw1, 2, and 3 Specificities. In: Albert, E.D., et al. Histocompatibility Testing 1984. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69770-8_136
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DOI: https://doi.org/10.1007/978-3-642-69770-8_136
Publisher Name: Springer, Berlin, Heidelberg
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