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The Second Complement Component, C2, in the Ninth Workshop

  • W. H. Marshall
  • M. Neugebauer
  • M. P. Baur
  • E. D. Albert

Abstract

Since the invention of the hemolytic overlay technique to reveal the presence of C2 in gels after isoelectric focusing [1, 4, 5], studies have been made in several populations [reviewed in 6], initially in Caucasoids and latterly in Mongoloids. In all groups studied, polymorphism of C2 has been shown. In Caucasoids there is one common allele, C2*l, which accounts for some 96% of C2 genes, and a less common allele, C2*2 (or C2*B), which accounts for about 4%. There are then a few much rarer variants.

Keywords

Complement Region Founder Haplotype Human Major Histocompatibility Complex Class Complete Haplotype Diabetes Research Institute 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1984

Authors and Affiliations

  • W. H. Marshall
    • 1
  • M. Neugebauer
    • 2
  • M. P. Baur
    • 2
  • E. D. Albert
    • 3
  1. 1.Memorial University of NewfoundlandSt. John’sCanada
  2. 2.Biometrical DepartmentDiabetes Research InstituteDüsseldorfFederal Republic of Germany
  3. 3.Laboratory for Immunogenetics, Children’s PolyclinicUniversity of MunichMunich 2Federal Republic of Germany

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