The Second Complement Component, C2, in the Ninth Workshop

  • W. H. Marshall
  • M. Neugebauer
  • M. P. Baur
  • E. D. Albert


Since the invention of the hemolytic overlay technique to reveal the presence of C2 in gels after isoelectric focusing [1, 4, 5], studies have been made in several populations [reviewed in 6], initially in Caucasoids and latterly in Mongoloids. In all groups studied, polymorphism of C2 has been shown. In Caucasoids there is one common allele, C2*l, which accounts for some 96% of C2 genes, and a less common allele, C2*2 (or C2*B), which accounts for about 4%. There are then a few much rarer variants.


Complement Region Founder Haplotype Human Major Histocompatibility Complex Class Complete Haplotype Diabetes Research Institute 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1984

Authors and Affiliations

  • W. H. Marshall
    • 1
  • M. Neugebauer
    • 2
  • M. P. Baur
    • 2
  • E. D. Albert
    • 3
  1. 1.Memorial University of NewfoundlandSt. John’sCanada
  2. 2.Biometrical DepartmentDiabetes Research InstituteDüsseldorfFederal Republic of Germany
  3. 3.Laboratory for Immunogenetics, Children’s PolyclinicUniversity of MunichMunich 2Federal Republic of Germany

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