Skip to main content
SpringerLink
Log in
Book cover

Chirurgische Onkologie pp 166–181Cite as

Prinzipien der lokalen Chemotherapie und Hyperthermie

  • Chapter

  • 38 Accesses

Part of the book series: Die Praxis der Chirurgie ((PRAXCHIR))

Zusammenfassung

Die häufigsten malignen Tumoren, insbesondere jene des Gastrointestinaltrakts, weisen auch heute noch eine geringe Empfindlichkeit gegenüber systemischer Chemotherapie auf. Deshalb wurde bereits seit den 50er Jahren versucht, durch örtliche Anwendung eine bessere Wirksamkeit zu erzielen, wenn eine chirurgische und/oder Strahlentherapie unmöglich ist.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   54.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Ackerman NB (1982) The blood supply of liver metastases. In: Weiss L, Gilbert HG (eds) Liver metastasis. Hall, Boston, pp 96–125

    Google Scholar 

  • Aigner K, Walter H, Tonn JC, Krahl M, Wenzl A, Merker G, Schwemmle K (1982) Die isolierte Leberperfusion mit 5-FU beim Menschen. Chirurg 53:571

    PubMed  CAS  Google Scholar 

  • Aigner K, Hild P, Henneking K, Paul E, Hundeiker M (1983 a) Regional perfusion with cis-platinum und dacar-bazine. In: Schwemmle K, Aigner K (eds) Vascular perfusion in cancer therapy. Springer, Berlin Heidelberg New York Tokyo, p 233

    Google Scholar 

  • Aigner K, Tonn JC, Hechtel R, Seuffer R (1983 b) Die intraarterielle Zytostatikatherapie mit venöser Filtration im halboffenen System. Onkologie 6:74

    PubMed  CAS  Google Scholar 

  • Ardenne M von (1972) Krebszellkinetik und Krebs-Mehrschritt-Therapie. Z Naturforsch 27b:1547

    Google Scholar 

  • Ariel IM, Padula G (1982) Treatment of asymptomatic metastatic cancer to the liver from primary colon and rectal cancer by the intraarterial administration of chemotherapy and radioactive isotopes. J Surg Oncol 20:151

    PubMed  CAS  Google Scholar 

  • Ausmann RK (1961) Development of a technique for isolation perfusion of the liver. NY State J Med 61:3993

    Google Scholar 

  • Aust JB, Ausmann RK (1960) The technique of liver perfusion. Cancer Treat Rep 10:23

    CAS  Google Scholar 

  • Banks MD, Pontes JE, Izbicke RM, Pierce JM (1977) Topical instillation of doxorubicinhydrochloride in the treatment of recurrent superficial transitional cell carcinoma of the bladder. J Urol 118:757

    PubMed  CAS  Google Scholar 

  • Barone RM, Byfield JE, Goldfarb PB, Frankel S, Ginn C, Greer S (1982) Intra-arterial chemotherapy using an implantable infusion pump and liver irradiation for the treatment of hepatic metastases. Cancer 50:850

    PubMed  CAS  Google Scholar 

  • Bengmark S, Jeppsson B (1983) Die kombinierte Behandlung von Lebertumoren mit intermittierender Desarteria-lisierung und intraarterieller Zytostatikainfusion. In: Schwemmle K, Aigner K (eds) Vascular perfusion in cancer therapy. Springer, Berlin Heidelberg New York Tokyo, p 68

    Google Scholar 

  • Bengmark S, Rosengren K (1970) Angiographie study of the collateral circulation to the liver after ligation of the hepatic artery in man. Am J Surg 119:620

    PubMed  CAS  Google Scholar 

  • Biskoping J, Hempelmann G (1983) Anaesthesia for isolated liver perfusion in man. In: Schwemmle K, Aigner K (eds) Vascular perfusion in cancer therapy. Springer, Berlin Heidelberg New York, Tokyo, p 110

    Google Scholar 

  • Boddie AW, Booker L, Mullins JD, Buckley CJ, McBride CM (1978) Hepatic hyperthermia by total isolation and regional perfusion in vivo. J Surg Oncol 26:447

    Google Scholar 

  • Breithaupt H, Aigner K, Hechtel R (1983) Kinetics of MTX, DTIC and 5-FU during isolated liver perfusion. In: Schwemmle K, Aigner K (eds) Vascular perfusion in cancer therapy. Springer, Berlin Heidelberg New York Tokyo, p 116

    Google Scholar 

  • Bremer MH, Campos LT, Sinkovics J (1981) Permanent subcutaneous subclavian catheters. ASCO abstr. Nr. C-328, p 416

    Google Scholar 

  • Buchwald H, Grage TB, Vassilopoulos PP, Rodhe TD, Varco RL, Blackshear PJ (1980) Intraarterial infusion chemotherapy for hepatic carcinoma using a totally implantable infusion pump. Cancer 45:866

    PubMed  CAS  Google Scholar 

  • Bücheier E, Vogel H, Hyn W (1980) Die verschiedenen Oc-clusionsmethoden und ihre spezifische Anwendung. In: Anacker H, Gulotta U, Rapp N (eds) Percutaneous biopsy and therapeutic vascular occlusion. Thieme, Stuttgart New York London

    Google Scholar 

  • Burgener FA (1980) Peripheral hepatic artery embolisation in rabbits with VX2 carcinomas of the liver. Cancer 46:56

    PubMed  CAS  Google Scholar 

  • Cady B (1973) Hepatic arterial patency and complications after catheterisation for infusion chemotherapy. Am J Surg 178:156

    CAS  Google Scholar 

  • Calvo DB, Patt YZ, Chuang VP et al. (1980) Phase III trial of percutaneous intraarterial Cis-diamminedichloro-platinum (II) for regionally confined malignancy. Cancer 45:1278

    PubMed  Google Scholar 

  • Casper ES, Kelsen DP, Alcock NW, Lewis JL Jr (1982) Pharmacokinetic study of intraperitoneal (IP) cisplatin (CP) in patients with malignant ascites. ASCO abstr. N.C. 87, p 22

    Google Scholar 

  • Cavaliere R, Ciocatto EC, Giovanella BC et al. (1967) Selective heat sensitivity of cancer cells. Cancer 20:1351

    PubMed  CAS  Google Scholar 

  • Chahinian AP (1982) Malignant mesothelioma. In: Holland JF, Frei III E (eds) Cancer medicine, 2nd edn. Lea & Febiger, Philadelphia, p 1744

    Google Scholar 

  • Chen HSG, Gross JF (1980) Intraarterial infusion of anticancer drugs: Theoretic aspects of drug delivery and review of responses. Cancer Treat Rep 64:31

    PubMed  CAS  Google Scholar 

  • Clouse ME, Ahmed R, Ryan RB, Oberfield RA, McCaffrey JA (1977) Complications of longterm transbrachial hepatic arterial infusion chemotherapy. AJR 129:799

    PubMed  CAS  Google Scholar 

  • Cohen AM, Wood WC, Greenfield A, Waltmann A, Dedrick C, Blackshear PJ (1980) Transbrachial hepatic arterial chemotherapy using an implanted infusion pump. Dis Colon Rectum 23:223

    PubMed  CAS  Google Scholar 

  • Creech O Jr, Krementz ET, Ryan RF, Winblad JN (1958) Chemotherapy for cancer. Ann Surg 148:616

    PubMed  Google Scholar 

  • Creech O, Krementz ET, Ryan RF, Reemtsma K, Winblad JN (1959) Experiences with isolation perfusion techniques in the treatment of cancer. Ann Surg 149:627

    PubMed  Google Scholar 

  • Dakhil S, Ensminger WD, Cho K, Niederhuber J, Doan K, Wheeler R (1982) Improved regional selectivity of hepatic arterial BCNU with degradable microspheres. Cancer 50:631

    PubMed  CAS  Google Scholar 

  • Dick R (1978) Transcatheter embolisation in liver disease. Br J Radiol 51:601

    Google Scholar 

  • Dickson JA, Suzangar M (1976) A predictive in vitro assay for the sensitivity of human solid tumours to hyperthermia (42° C) and its value in patient management. Clin Oncol 2:141

    PubMed  CAS  Google Scholar 

  • Dietzel F (1978) Thermo-radio-therapy. Urban & Schwarzenberg, München Wien Baltimore

    Google Scholar 

  • Dietzel F (1983) Basic principles in hyperthermic tumour therapy. In: Schwemmle K, Aigner K (eds) Vascular perfusion in cancer therapy. Springer, Berlin Heidelberg New York Tokyo, p 178

    Google Scholar 

  • Dollinger M (1982) The role of aggressive management of liver metastases in a community hospital. In: Weiss L, Gilbert HA (eds) Liver metastasis. Hall, Boston, p 365

    Google Scholar 

  • Eckman WW, Patlak CS, Fenstermacher JD (1974) A critical evaluation of principles governing the advantages of intraarterial infusions. J Pharmacokinet Biopharm 2:257

    PubMed  CAS  Google Scholar 

  • El-Domeiri AA (1976) A method of intermitted occlusion and chemotherapy infusion of the hepatic artery. Surg Gynecol Obstet 143:107

    PubMed  CAS  Google Scholar 

  • El-Domeiri AA (1980) Treatment of hepatic metastases in cancer of the colon and rectum. A preliminary report. Cancer 45:2245

    PubMed  CAS  Google Scholar 

  • Ensminger WD, Gyves JW (1983) Clinical pharmacology of intraarterial chemotherap. Semin Oncol 10/2:176

    PubMed  CAS  Google Scholar 

  • Ensminger WD, Rosowsky A, Raso V et al. (1978) A clinical-pharmacological evaluation of hepatic arterial infusions of 5-fluoro-2′-deoxyuridine and 5-fluorouracil. Cancer Res 38:3784

    PubMed  CAS  Google Scholar 

  • Ensminger W, Niederhuber J, Dakhil S, Thrall J, Wheller R (1981) Totally implanted drug delivery system for hepatic arterial chemotherapy. Cancer Treat Rep 65:393

    PubMed  CAS  Google Scholar 

  • Fabrizius HA, Stahn R, Metzger B, Bluck K, Engelhardt R, Neumann H, Selling D (1978) Changes in cellular immunological functions of healthy adults induced by one-hour 40° C hyperthermia. In: Streffer C (ed) Cancer therapy by hyperthermia and radiation. Urban & Schwarzen-berg, München Wien Baltimore, p 309

    Google Scholar 

  • Fazekas JT, Nerlinger RE (1981) Localized hyperthermia adjuvant to irradiation in superficial recurrent carcinomas: A preliminary report on 46 patients. Int J Radiat Oncol Biol Phys 7:1457

    PubMed  CAS  Google Scholar 

  • Field SB (1978) The response of normal tissues to hyperthermia alone or in combination with X-rays. In: Streffer C (ed) Cancer therapy by hyperthermia and radiation. Urban & Schwarzenberg, München Wien Baltimore, p 37

    Google Scholar 

  • Fortner JG (1976) A new method for long term intrahepatic chemotherapy. Surg Gynecol Obstet 143:979

    PubMed  CAS  Google Scholar 

  • Freeman ML, Dewey WC, Hopwood LE (1977) Enhancement of thermal damage by acidic milieu. Radiat Res 70:612

    Google Scholar 

  • Freilinger G, Cerny C, Coraim F et al. (1976) Die Mehrschritt-Therapie des Melanomalignoms. Langenbecks Arch Chir 342:549

    PubMed  CAS  Google Scholar 

  • Friedman MA, Philips TL, Carter SK, Sonoda T, Hannigan JF Jr (1982) Radiation and chemotherapy (intraarterial vs. intravenous) for liver tumours. ASCO abst. Nr. C 359, p 93

    Google Scholar 

  • Gerweck L, Rottinger E (1976) Enhancement of mammalian cell sensitivity of hyperthermia by pH alteration. Radiat Res 67:508

    PubMed  CAS  Google Scholar 

  • Ghussen F, Nagel K, Groth W (1981) Regionale hyper-therme Zytostatikaperfusion bei malignen Melanomen der Extremitäten. Dtsch Med Wochenschr 106:1612

    PubMed  CAS  Google Scholar 

  • Goldman ML, Bilbao MK, Rösch J, Dotter CT (1975) Complications of indwelling chemotherapy catheters. Cancer 36:1983

    Google Scholar 

  • Goodman LE, Seligman AN, Calabresi P (1982) Regional chemotherapy. In: Holland JF, Frei III E (eds) Cancer medicine, 2nd edn. Lea & Febiger, Philadelphia, p 752, 2288

    Google Scholar 

  • Goldstein HM, Wallace S, Anderson JH, Bree RL, Giantarco C (1976) Transcatheter occlusion of abdominal tumours. Radiology 120:539

    PubMed  CAS  Google Scholar 

  • Gyves J, Ensminger W, Niederhuber J et al. (1982) Phase I study of intraperitoneal (IP) 5 day continuous 5-FU infusion and bolus Mitomycin C. ASCO abst. C-59, p 15

    Google Scholar 

  • Hahn GM (1978) Interactions of drugs and hyperthermia in vitro and in vivo. In: Streffer C (ed) Cancer therapy by hyperthermia and radiation. Urban & Schwarzenberg, München Wien Baltimore, p 72

    Google Scholar 

  • Hardy TG, Hartmann RF, Samson RB, Stewart WRC, Aguilar PS (1982) Percutaneous intrahepatic chemotherapy via indwelling portal vein catheter and subcutaneous injection reservoir. Dis Colon Rectum 25:292

    PubMed  Google Scholar 

  • Har-Kedar I, Bleehen NM (1976) Advances in radiation biology. Academic Press, New York, p 229

    Google Scholar 

  • Herbst M, Bernhardt J (1982) Temperature distributions produced by 13,56 MHz EM radiation in various phantoms. Br J Cancer [Suppl 5] 45:41

    Google Scholar 

  • Herbst M, Sauer R (1983) Zur Tumorbehandlung mit Hyperthermie und Radiotherapie. Strahlentherapie 159:93

    PubMed  CAS  Google Scholar 

  • Howell SB, Pfeifle CE, Wung WE, Olshen RA (1982) Intraperitoneal chemotherapy with cis-platin (DDP). ASCO abstr. Nr. C 107, p 27

    Google Scholar 

  • Jaffe N, Chuang V, Wallace S, Ayala A, Murray J, Romsdahl M, Benjamin RS (1980) Osteosarcoma: Control of the primary tumour with intra-arterial cis-diaminochlorid platinum II (IACDP). ASCO abstr. 791, p 197

    Google Scholar 

  • Jaffe N, Ayala A, Wang YM et al. (1981) Pharmacodynamics, drug concentration and histology of osteosarcoma following treatment with intra-arterial cis-platinum (I ACDP). ASCO abstr. C 265, p 400

    Google Scholar 

  • Jochimsen PR, Zike WL, Shirazi SS, Pearlman NW (1978) Iatrogenic liver abscesses. Arch Surg 113:141

    PubMed  CAS  Google Scholar 

  • Kato T, Nemoto R, Mori H, Takahashi M, Tamakawa Y (1981) Transcatheter arterial chemoembolisation of renal cell carcinoma with microencapsuled mitomycin C. J Urol 125:19

    PubMed  CAS  Google Scholar 

  • Kim DK, Penneman R, Kalium B, Carillo M, Scheiner E, Fortner JG (1976) Acute renal failure after ligation of the hepatic artery. Surg Gynecol Obstet 143:391

    PubMed  CAS  Google Scholar 

  • Kim DK, Watson RC, Pahnke LD, Fortner JG (1977) Tumour vascularity as a prognostic factor for hepatic tumours. Ann Surg 185:31

    PubMed  CAS  Google Scholar 

  • Krauß J (1981) Die regionale zytostatische Perfusion an der Chirurgischen Universitätsklinik Halle. Zentralbl Chir 106:53

    Google Scholar 

  • Krementz ET, Carter RD, Sutherland CM, Campbell M (1979) The use of regional chemotherapy in the management of malignant melanoma. World J Surg 3:289

    PubMed  CAS  Google Scholar 

  • Lange J, Zänker KS, Siewert JR et al. (1983) Extrakorporal induzierte Ganzkörperhyperthermie bei konventionell inkurablen Malignompatienten. Dtsch Med Wochenschr 108:504

    PubMed  CAS  Google Scholar 

  • Lehane DE, Zubler MA, Lane M, Smith FE (1982) Intraarterial cisplatin in metastatic or recurrent colon cancer. ASCO abstr. C 365, p 94

    Google Scholar 

  • Lokich J, Kinsella T, Perri J, Malcolm A, Cluse M (1981) Concomittant hepatic radiation and intra-arterial fluori-nated pyrimidine therapy. Cancer 48:2569

    PubMed  CAS  Google Scholar 

  • Lokich J, Ensminger W (1983) Ambulatory pump infusion devices for hepatic artery infusion. Semin Oncol 10/2:183

    PubMed  CAS  Google Scholar 

  • Lundberg BW (1977) Intraarterial chemotherapy. In: Bekker FF (ed) Cancer, Vol 5. Plenum, New York London, p 191

    Google Scholar 

  • Marmor JB, Pounds D, Hahn G (1978) Clinical trial of ultrasound (S) induced local hyperthermia. ASCO abstr. 330

    Google Scholar 

  • Mavligit GM, Benjamin R, Patt YZ et al. (1981) Intra-arterial cis-platin for patients with inoperable scelettal tumours. Cancer 48, 1

    PubMed  CAS  Google Scholar 

  • McBride CM (1974) Sarcomas of the limbs. Results of adjuvant chemotherapy using isolation perfusion. Arch Surg 109:304

    PubMed  CAS  Google Scholar 

  • Merker G, Helling HJ, Krahl M, Aigner K (1983) Electron microscopical findings after isolated liver perfusion. In: Schwemmle K, Aigner K (eds) Vascular perfusion in cancer therapy. Springer, Berlin Heidelberg New York Tokyo, p 103

    Google Scholar 

  • Moertel C (1982) The peritoneum. In: Holland JF, Frei III E (eds) Cancer medicine, 2nd edn. Lea & Febiger, Philadelphia, p 1863

    Google Scholar 

  • Morton DL, Eilber FR (1982) Soft tissue sarcomas. In: Holland JF, Frei III E (eds) Cancer medicine, 2nd edn. Lea & Febiger, Philadelphia, p 2141, 2404

    Google Scholar 

  • Norell H, Wilson C (1967) Brain tumour chemotherapy with methotrexate given intrathecally. JAMA 201:93

    Google Scholar 

  • Oberfield RA, McCoffrey JA, Polio J, Clouse ME, Hamilton H (1979) Prolonged and continuous percutaneous intraarterial infusion chemotherapy in advanced metastatic liver adenocarcinoma from colorectal primary. Cancer 44:414

    PubMed  CAS  Google Scholar 

  • Okamura J, Horikawa S, Fujiama T et al. (1982) An appraisal of transcatheter arterial embolisation combined with transcatheter arterial infusion of chemotherapeutic agent for hepatic malignancies. World J Surg 6:352

    PubMed  CAS  Google Scholar 

  • Order SE, Leibel SA (1982) Combined hepatic irradiation and misonidazole for palliation of liver metastases. In: Weiss L, Hall GK (eds) Liver metastasis. Hall, Boston, p 360

    Google Scholar 

  • Overgaard J (1977) Effect of hyperthermia on malignant cells in vivo. Cancer 39:2637

    PubMed  CAS  Google Scholar 

  • Patt YZ, Mavligit GM, Chuang VP et al. (1980) Percutaneous hepatic arterial infusion (HAI) of mitomycin C and floxuridine (FUDR) an effective treatment for metastatic colorectal carcinoma in the liver. Cancer 46:261

    PubMed  CAS  Google Scholar 

  • Perri J, Erikson KA (1983) Nursing issues for hepatic arterial infusion therapy. Semin Oncol 2:191

    Google Scholar 

  • Pettavel J (1983) Arterial infusion chemotherapy for hepatic metastases. In: Schwemmle K, Aigner K (eds) Vascular perfusion in cancer therapy. Springer, Berlin Heidelberg New York Tokyo, p 63

    Google Scholar 

  • Pettigrew RT, Ludgate CM, Gee AP, Smith AN (1978) Whole-body hyperthermia combined with chemotherapy in the treatment of advanced human cancer. In: Streffer C (ed) Cancer therapy by hyperthermia and radiation. Urban & Schwarzenberg, München Wien Baltimore, p 337

    Google Scholar 

  • Reinhold HS, van der Berg-Block A (1981) Enhancement of thermal damage to the microcirculation of sandwich tumours by additional treatment. Eur J Cancer Clin Oncol 17:81

    Google Scholar 

  • Rosen G, Marcove R, Caparros B, Nierenberg A, Kosloff C, Huvos A (1979) Primary osteogenic sarcoma; the rationale for praeoperative chemotherapy and delayed surgery. Cancer 43:2163

    PubMed  CAS  Google Scholar 

  • Sako M, Yokogawa S, Sakomoto K, Hirota S., Okada S, Murao S (1982) Transcatheter microembolisation with ferropolysaccharide. A new approach to ferromagnetic embolisation of tumours: Preliminary report. Invest Radiol 17:573

    PubMed  CAS  Google Scholar 

  • Schepke P, Wopfner F (1982) Superselektive arterielle Tu-morangiographie und Chemotherapie. Röntgenblätter 5:191

    Google Scholar 

  • Schultheiss KH (1983) Chemoembolisation — a new treatment of malignant tumours and metastases. In: Schwemmle K, Aigner K (eds) Vascular perfusion in cancer therapy. Springer, Berlin Heidelberg New York Tokyo, p 46

    Google Scholar 

  • Selawry OS, Hansen HH (1982) Lung cancer. In: Holland JF, Frei III E (eds) Cancer medicin, 2nd edn. Lea & Febiger, Philadelphia, p 1709

    Google Scholar 

  • Shedd DP (1982) Cancer of the head and neck. In: Holland JF, Frei III E (eds) Cancer medicin, 2nd edn. Lea & Febiger, Philadelphia, p 2373

    Google Scholar 

  • Sherman DM, Weichselbaum RR (1982) Hepatic metastasis: The role of radiotherapy. In: Weiss L, Gilbert HA (eds) Liver metastasis. Hall, Boston, p 337

    Google Scholar 

  • Silva YJ (1979) In vivo use of human umbilical vessels and the ductus venosus Arantii. Surg Gynecol Obstet 148:595

    PubMed  CAS  Google Scholar 

  • Speyer JL, Collins JM, Dedrick BL et al. (1980) Phase I and pharmacology studies of 5-FU administrated intrape-ritoneally. Cancer Res 40:567

    PubMed  CAS  Google Scholar 

  • Stehlin J, Clark RC, White E, Smith JL, Griffin AC, Jesse RH, Healey JE (1969) Regional chemotherapy for cancer. Ann Surg 151:605

    Google Scholar 

  • Stehlin JS, Giovanella BC, de Ipolyi PD, Anderson RF (1979) Eleven years experience with hyperthermic perfusion for melanoma of the extremities. World J Surg 3:305

    PubMed  Google Scholar 

  • Stephens FO (1983 a) Pharmakokinetics of intra-arterial chemotherapy. In: Schwemmle K, Aigner K (eds) Vascular perfusion in cancer therapy. Springer, Berlin Heidelberg New York Tokyo, p 1

    Google Scholar 

  • Stephens FO (1983b) Clinical experience in the use of intraarterial infusion chemotherapy in the treatment of cancers in the head and neck, the extremities, the breast and the stomach. In: Schwemmle K, Aigner K (eds) Vascular perfusion in cancer therapy. Springer, Berlin Heidelberg New York Tokyo, p 122

    Google Scholar 

  • Storm FK, Morton DL (1983) Hyperthermia: Adjunctive modality for hepatic infusion chemotherapy. Semin Oncol 2:223

    Google Scholar 

  • Taylor J, Bennet R, Sherrif S (1979) The blood supply of colorectal liver metastases. Br J Cancer 39:749

    Google Scholar 

  • Taylor J, Brooman P, Rowling JT (1977) Adjuvant liver perfusion in colorectal cancer: Initial results of a clinical trial. Br Med J 2:1320

    PubMed  CAS  Google Scholar 

  • Tilchen E, Patt YZ, McBride CM, Wallace S, Chuang V, Mavligit GM (1981) Sequence of regional chemotherapy and surgery. Arch Surg 116:959

    PubMed  CAS  Google Scholar 

  • Tonak J (1981) Die hypertherme Zytostatikaperfusion beim malignen Melanom. In: Nagel G, Sauer R, Schreiber HW (Hrsg) Aktuelle Onkologie, Bd 1. Zuckschwerdt, München

    Google Scholar 

  • Tonak J, Hohenberger W, Göhl J (1984) Die isolierte hypertherme Extremitätenperfusion bei malignen Melanomen und Weichteilsarkomen. Chirurg 55:499

    PubMed  CAS  Google Scholar 

  • Urist MM, Balch CM (1982) A totally implantable drug infusion pump for metastatic colorectal carcinoma to the liver. Proc. 31th Int Congr Seattle, abst. Nr. 2637, p 462

    Google Scholar 

  • Van Voorthuisen AE, Herben MG, Pauwels EK (1980) Transaxillary intra-arterial treatment of hepatic metastases with cytostatica and embolisation; its control by isotope studies. Excerpta Med Int Congr Ser 522:242

    Google Scholar 

  • Walker MD (1982) Brain and peripheral nervous system tumours. In: Holland JF, Frei III E (eds) Cancer medicin, 2nd edn. Lea & Febiger, Philadelphia, p 1603

    Google Scholar 

  • Wallace S, Chuang P (1983) Transcatheter management of the cancer patient. In: De Vita VT, Hellmann S, Rosenberg SA (eds) Principles and practice of oncology. Lippincot, Philadelphia Toronto, p 1862

    Google Scholar 

  • Watkins E, Khazei AM, Nahra KS (1970) Surgical basis for arterial infusion chemotherapy of disseminated carcinoma of the liver. Surg Gynecol Obstet 130:581

    PubMed  Google Scholar 

  • Weigand H, Stahlschmidt M, Fischer J (1983) The transumbilical portal vein catheterisation for intrahepatic chemotherapy. In: Schwemmle K, Aigner K (eds) Vascular perfusion in cancer therapy. Springer, Berlin Heidelberg New York Tokyo, p 90

    Google Scholar 

  • Weisschedel U, Wieland C (1981) Kombinierte Wärme-Strahlentherapie maligner Tumoren. Onkologie 4:6

    Google Scholar 

  • Wopfner F (1981) Therapie inoperabler Lebermetastasen. Dtsch Med Wochenschr 106:1099

    PubMed  CAS  Google Scholar 

Download references

Authors
  1. F. Wopfner
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. Tonak
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. P. Schepke
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Chirurgische Klinik der Universität Erlangen-Nürnberg, Maximiliansplatz, 8520, Erlangen, Deutschland

    Franz Paul Gall (Prof. Dr. med.) (Prof. Dr. med.)

  2. Abteilung für Klinische Pathologie, Chirurgische Universitätsklinik, Maximiliansplatz, 8520, Erlangen, Deutschland

    Paul Hermanek (Prof. Dr. med.) (Prof. Dr. med.)

  3. Chirurgische Abteilung, Städtisches Krankenhaus, Spitalstraße 4, 8550, Forchheim, Deutschland

    Jürgen Tonak (Priv.-Doz. Dr. med.) (Priv.-Doz. Dr. med.)

Rights and permissions

Reprints and permissions

Copyright information

© 1986 Springer-Verlag Berlin · Heidelberg

About this chapter

Cite this chapter

Wopfner, F., Tonak, J., Schepke, P. (1986). Prinzipien der lokalen Chemotherapie und Hyperthermie. In: Gall, F.P., Hermanek, P., Tonak, J. (eds) Chirurgische Onkologie. Die Praxis der Chirurgie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69600-8_10

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-69600-8_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-69601-5

  • Online ISBN: 978-3-642-69600-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation