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Calcium Antagonists

  • Chapter
Clinical Pharmacology of Antianginal Drugs

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 76))

Abstract

Since their clinical introduction in the early 1970s in Japan and Europe calcium antagonists have enjoyed great interest in the cardiological community. This is undoubtedly due to the fact that they are an entirely new group of compounds with a novel therapeutic principle, the blocking of calcium ions from entering the cell’s interior. GEvers (1981), who has aptly called calcium the “managing director”, thus emphasized their significance, for “who would dare to block the entry of the director!” Thus far, these drugs have indeed been shown to have great clinical efficacy for several difficult syndromes and diseases.

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  1. P. G. Hugenholtz
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    Ulrich Abshagen (Leiter Produktentwicklung Therapeutica) (Leiter Produktentwicklung Therapeutica)

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Hugenholtz, P.G. (1985). Calcium Antagonists. In: Abshagen, U. (eds) Clinical Pharmacology of Antianginal Drugs. Handbook of Experimental Pharmacology, vol 76. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69524-7_13

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  • DOI: https://doi.org/10.1007/978-3-642-69524-7_13

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